background: single-nucleotide polymorphism (snp) rs2476601 within protein tyrosine phosphatase non-receptor type 22 gene (ptpn22) has been shown to be a risk factor for different autoimmune diseases. this study explored the association of 1858 c/t snp with rheumatoid arthritis (ra) and celiac disease (cd) in a region covering south-west of iran. methods: totally, 52 patients with cd, 120 patien...

objective: anti-cyclic citrullinated peptide (anti-ccp) antibodies are highly specific markers for rheumatoid arthritis (ra) and useful for predicting rheumatoid arthritis (ra) development and progression. we assessed the diagnostic value of anti-ccp antibodies in our patients with ra. materials and methods: anti-ccp antibodies and rheumatoid factor (rf) titers were determined in 247 serum sam...

Rheumatoid arthritis (RA) is a chronic inflammatory joint disease with different extra-articular manifestations. Among those extra-articular manifestations, there are significant cutaneous manifestations which may result in first admission to a dermatologist. In this article some specific and non-specific skin lesions of RA such as rheumatoid nodules, exacerbated nodules, rheumatoid vascu...

Background: Previous studies showed that one of the complications of rheumatoid arthritis disease was auditory disorder. The goal of the present study was to compare the auditory status in patients with rheumatoid arthritis and healthy individuals. Methods: In the present case-control study, 30 normal persons and 60 persons with rheumatoid arthritis with mean age of 46.72 and standard deviatio...

rheumatoid factors (rf) are autoantibodies with specificity for the fc portion of human igg. production of rf is a characteristic feature of rheumatoid arthritis (ra) and is detectable in high titer in about 90% of these patients. in this study, we measured total igm, iga, igmrf and igarf in serum and synovial fluid of 45 ra patients by elisa and the results were compared with those obtained by...

background: this study aimed to compare the percentage of detection of periarthritis in patients with rheumatoid arthritis using clinical examination and ultrasound methods. materials and methods: this study is a cross?sectional study which was conducted in al?zahra hospital (isfahan, iran) during 2014–2015. in our study, ninety patients were selected based on the american college of rheumatolo...

background: there is a hypothesis that people with rheumatoid arthritis (ra) can also be at risk of periodontal disease. this study aimed to assess the periodontal health in patients with and without rheumatoid arthritis. methods and materials: thirty ra patients with ra and 30 healthy individuals without ra were included. information regarding demographic characteristics and periodontal parame...

Background: The relationship between rheumatoid arthritis and poor oral hygiene has longbeen proven. Colonization of Porphyromonas gingivalis in the oral cavity can play an important role in rheumatoid arthritis. The aim of this study was to determine whether there is a relationship between rheumatoid arthritis disease and the presence of P. gingivalis. <stro...