*Corresponding author: Mohamed Fawzy Ramadan, Associate Professor, Biochemistry Department, Faculty of Agriculture, Zagazig University, Zagazig 44519, Zagazig, Egypt. Tel: +20-055-2320282, 002-055-2313940 Fax: +20-055 2287567, 002-055-2345452 E-mail: [email protected] or [email protected] Foundation Project: Supported by Faculty of Agriculture, Zagazig University (Project Number 34-2...

1-[(2-adamantyl)amino]acetyl-2-cyano-(S)-pyrrolidine, monohydrochloride (PKF275-055), a vildagliptin analog, is a novel, selective, potent, orally bioavailable, and long-acting dipeptidyl peptidase IV inhibitor. We studied the effect of PKF275-055 administration on the prevention, protection, and treatment of diabetic neuropathy in the streptozotocin-induced diabetic rat. PKF275-055 improved bo...

The question of whether object representations in the human brain are objectcentered or viewer-centered has motivated a variety of experiments with divergent results. A key issue concerns the visual recognition of objects seen from novel views. If recognition performance depends on whether a particular view has been seen before, it can be interpreted as evidence for a viewer-centered representa...

We compute complete leading logarithms in Φ4 theory with the help of Connes and Kreimer RG equations. These equations are defined in the Lie algebra dual to the Hopf algebra of graphs. The results are compared with calculations in parquet approximation. An interpretation of the new RG equations is discussed.

Valerie NOVITZKÁ, Anita VERBOVÁ Department of Computers and Informatics, Faculty of Electrical Engineering and Informatics, Technical University of Košice, Letná 9, 042 00 Košice, tel. 055/602 4182, E-mail: [email protected] ** Department of Computers and Informatics, , Faculty of Electrical Engineering and Informatics, Technical University of Košice, Letná 9, 042 00 Košice, tel. 055/602...

Inhibitors of dipeptidyl peptidase-4 (DPP-IV), a key regulator of the actions of incretin hormones, exert antihyperglycemic effects in type 2 diabetic patients. A major question concerns the potential ability of long term DPP-IV inhibition to have beneficial disease-modifying effects, specifically to attenuate loss of pancreatic β-cell mass due to oxidative stress induced inflammation. Here, we...

Previous studies demonstrated that analogs of benztropine (BZT) possess high affinity for the dopamine transporter, inhibit dopamine uptake, but generally have behavioral effects different from those of cocaine. One hypothesis is that muscarinic-M(1) receptor actions interfere with cocaine-like effects. Several tropane-nitrogen substitutions of 4',4"-diF-BZT have reduced M(1) affinity compared ...