background: all-trans retinol is a biological antioxidantscavenging the ros in the cell culture. objectives: this studywas conducted to investigate the effect of all-trans retinol infertilization and culture medium on mouse embryo's developmentalcompetence. methods: this study was designed into twoexperiments. in the first experiment, in vitro mature oocytes wereco-cultured with sperm in fertil...

BACKGROUND: All-trans retinol is a biological antioxidantscavenging the ROS in the cell culture. OBJECTIVES: This studywas conducted to investigate the effect of all-trans retinol infertilization and culture medium on mouse embryo's developmentalcompetence. METHODS: This study was designed into twoexperiments. In the first experiment, in vitro mature oocytes wereco-cultured with sperm in fertil...

Amaç: Retinol fetusta birçok organın gelişimi için gereklidir. Bu nedenle retinol eksikliği teratojenik etkilere neden olabilir. çalışmada çok düşük doğum ağırlıklı bebeklerde retinol, bağlayıcı protein (RBP) ve plasental transfer hızı düzeyleri ile prematüre retinopatisi (ROP) arasındaki ilişkiyi araştırmayı amaçladık. Gereç Yöntemler: Çalışma ocak-aralık 2020 tarihleri arasında prospektif koh...

background: oxidative stress in reproductive system leads to sperm dna damage and sperm membrane lipid peroxidation and may play an important role in the pathogenesis of male infertility, especially in idiopathic cases. antioxidants such as carotenoids function against free radical damages. objective : the aim of this study was to determine the levels of lycopene, beta-carotene and retinol in s...

Vitamin A is the generic name given to a group of fat-soluble compounds including retinol (the alcohol form), retinyl esters, retinaldehyde and retinol acid. Deficiency, first recognized in 1912, can damage the epithelial cells lining the respiratory tract. It can also affect immunocompetence, the reproductive function, growth and vision. The dose of vitamin A for neonates is 5,000 IU given int...

Objective: Immunoglobulin A vasculitis (IgAV) is the most common systemic seen in children. The aim of this study to investigate relationship between malondialdehyde-induced oxidative stress, antioxidant system and organ involvement IgAV patients. Method: 32 patients 28 healthy children were included study. Serum malondialdehyde, reduced glutathione, vitamin E, C, retinol, beta-carotene levels ...

Retinol (vitamin A alcohol) is involved in the proper differentiation of epithelia. The mechanism of this involvement is unknown. We have previously reported that purified cellular retinol-binding (CRBP) will mediate specific binding of retinol to nuclei isolated from rat liver. We now report that pure CRBP delivers retinol to the specific nuclear binding sites without itself remaining bound. T...

Serum vitamin A homeostasis was studied in rats with nonfiltering kidneys prepared by ligation of renal arteries. Within 1-2 h of acute renal failure, the serum retinol level increased by 11-73% and was maintained for at least 4 h. More than 90% of the increase in serum retinol was associated with retinol in the retinol binding protein-transthyretin (RBP-TTR) complex. The activities of acyl-CoA...

The fluorescence yield of bound retinol in human retinolbinding protein (RBP) and irs prealbumin complex (PARBP) were found to be nearly the same and to exceed that of free retinol in petroleum ether by about 9-fold. Bovine serum albumin and P-lactoglobulin also formed strongly fluorescent water-soluble complexes with retinol. The fluorescence yield of retinol complexed with bovine serum albumi...

background: retinoids have been suggested to play a role in oogenesis and oocyte survival. objective: in the present study the effects of retinol palmitate were investigated on differential follicular counts in response to superovulation as well as follicle quality after vitrification of ovaries. materials and methods: ten, 4 week old female balb/c mice were randomly assigned to either paraffin...