how to cite this article: barzegar m, malaki m, sadegi-hokmabadi e. joubert syndrome with variable features: presentation of two cases. iran j child neurol. 2013  spring;7(2):43-46.   abstract joubert syndrome is a very rare disorder characterized by respiratory irregularities, nystagmus, hypotonia, and global developmental delay with abnormalities of cerebellum. we present two cases of this sy...

BACKGROUND Dysregulated respiratory control may play a role in the pathophysiology of panic disorder. This could be due to abnormalities in brain stem respiratory nuclei or to dysregulation at higher brain levels. Results from previous studies using the doxapram model of panic have yielded an unclear picture. A brief cognitive manipulation reduced doxapram-induced hyperventilation in patients, ...

Despite abundant research on the distribution of glottal stops and glottalization in English and other languages, it is still unclear which factors matter most in predicting where glottal stops occur. In this study, logistic mixed-effects regression modeling is used to predict the occurrence of word-initial full glottal stops vs. no voicing irregularity. The results indicate that prominence and...

Irregularity is an important aspect of the cardiovascular system dynamics. Numerical indices irregularity, such as largest Lyapunov exponent and correlation dimension estimated from interbeat interval time series, are early markers diseases. However, there no consensus on origin irregularity in system. A common hypothesis suggests importance nonlinear bidirectional coupling between respiratory ...

BACKGROUND AND PURPOSE To investigate the geometrical accuracy in proton beam therapy (PBT) to the lung by comparing the location of the fibrosis after PBT and the tumor using less invasive method. PATIENTS AND METHODS We examined 50 lung tumors that had been treated by respiratory-gated PBT (33-74 Gray equivalents). Image registration and re-slicing of computed tomography (CT) before and aft...

The El Niño/Southern Oscillation (ENSO) phenomenon is the dominant climatic fluctuation on interannual time scales. It is an irregular oscillation with a distinctive broadband spectrum. In this article, we discuss recent theories that seek to explain this irregularity. Particular attention is paid to explanations that involve the stochastic forcing of the slow ocean modes by fast atmospheric tr...

Dysregulation within both respiratory control systems and the hypothalamic-pituitary adrenal (HPA) axis has been implicated in the pathophysiological of panic disorder. However, potential linkages between respiration and the HPA axis have rarely been examined in panic patients. We have previously published neuroendocrine and psychophysiological response data from a laboratory panic model using ...