The aim of this study is to determine whether baicalin can be transferred along the olfactory pathway to the brain after nasal administration of baicalin phospholipid (BP) complex to rats, thereby circumventing the blood brain barrier. The concentration of baicalin in plasma and different brain tissues (olfactory bulb, cerebral cortex, striatum and cerebellum) were measured by high-performance ...

Results Fever and fatigue were frequent symptoms at onset, occurring respetively in 47 (45.1%) and 39 (37.5%) patients. The most common organ involvement was skeletal, affecting 89 (85.5%) of patients, 87 (97.7%) of whom were affected by non erosive arthritis. Jaccoud’s arthropathy was observed in 7 (6.7%) patients. Malar rash, leukopenia and non scarring alopecia were common findings. They occ...

The human P2X7 receptor is significant and exhibits several functions in neoplasia. At present, little is known with regard to its regulation. P2X7 expression may be regulated post-transcriptionally and putative microRNA (miRNA) binding sites are considered to be involved. The aim of this study was to determine whether miRNAs (miR-21, let-7 g and miR-205) regulate P2X7 mRNA stability. In additi...

Introduction:Orthodontic treatment is associted with a risk of root resorption.The aim of this study was to determine the risk of moderate and sever root resorption in orthodontic patients treated with fixed orthodontic appliance.   Method:A case-control study was performed on 70 orthodontic treated patients with moderate and sever root resorption and 70 controls matched for age,sex,duration ...

to shorten the dormancy period of potato minitubers and to increase a tuber's capacity to be planted sooner after being harvested, an experiment was conducted at pishtaz tissue culture company in karaj, using factorial experiment on the basis of a completely randomized design with three replications. the first factor was comprised of cultivars (agria, marfona and burren), the second minitu...