introduction: one of the most important agents in hospital-acquired infections is staphylococcus aureus. treatment of methicillin-resistant s. aureus (mrsa) infections with decreased susceptibility to vancomycin has recently been more difficult. the aim of this study was to evaluate the possible presence of vancomycin intermediate s. aureus (visa) and vancomycin- resistant s. aureus (vrsa) and ...

conclusions in the present study, we found a high prevalence of mrsa at the hospitals studied. the findings emphasized the increased prevalence of mrsa isolates containing different toxin and adhesion genes, probably accompanied by antimicrobial resistance. infection with such isolates worsens the clinical outcomes as well as the morbidity and mortality rates in hospitalized patients in icus. m...

Type 1 lipoteichoic acid (LTA) is present in many clinically important gram-positive bacteria, including enterococci, streptococci, and staphylococci, and antibodies against LTA have been shown to opsonize nonencapsulated Enterococcus faecalis strains. In the present study, we show that antibodies against E. faecalis LTA also bind to type 1 LTA from other gram-positive species and opsonized Sta...

conclusions resistance to oxacillin and other antibiotics was high, and most of the isolates were found to be multi-drug resistance (mdr). plasmid analysis of representative s. aureus isolates also demonstrates the presence of a wide range of plasmid sizes, with no consistent relationship between plasmid profiles and resistance phenotypes. regular surveillance of hospital infections and monitor...

background: the aim of this study was to compare the biofilm formation and the prevalence of biofilm-associated genes between the isolates of methicillin-resistant (mrsa) and methicillin-susceptible (mssa) staphylococcus aureus. methods: in total, 209 s. aureus isolates were collected. the antibiotic susceptibility test was conducted using nine antibiotics according to the guidelines of clinica...

conclusions these findings showed no significant difference regarding the presence of icaadbc genes between blood and wound isolates. background the polysaccharide intercellular adhesion (pia) produced by staphylococcus aureus is effective in the protection of isolates from outer harsh conditions and progress of infection. objectives the aim of this study was to compare the icaabcd genes encodi...

background and objectives: methicillin-resistant staphylococcus aureus (mrsa) is a major cause of nosocomial and community acquired infections. detection of mrsa in laboratories is very important for treatment and appropriate infection control. the aim of this study was to evaluate cefoxitin disk diffusion method for detection of mrsa and comparison of this method with other conventional method...

backgroundandobjectives:rapidandaccuratedetectionofmethicillinresistantstaphylococcus aureus (mrsa) is an important role of clinical microbiology laboratories to avoid treatment failure. the aim of this study was to compare conventional methods against the e-test minimum inhibitory concentration (mic) method to determine the best phenotypic method. materials and methods: methicillin resistance...

background protein a is the virulence factors of staphylococcus aureus rolling in its pathogenesis, and its gene is used for typing. polymerase chain reaction-restriction fragment length polymorphism (pcr-rflp) with different enzymes has been used for this action. objectives in this study, we used bsp143i enzyme for digestion of the gene, coding protein a (spa gene) in s. aureus. the bacteria w...

conclusions the relative higher frequency of some virulence genes in this study may reflect the emergence of isolates containing these genes in shiraz medical centers. background staphylococcus aureus is amongst major human pathogens both in hospitals and the community. this bacterium is an opportunistic pathogen responsible for a large number of self-limiting and even life-threatening diseases...