A mean residence time (MRT) is an important pharmacokinetic parameter. To the author's knowledge, however, a physiologically based structure of MRT (thereafter MRT structure) has not been published so far. Primarily this is because MRT structures cannot be identified by traditional pharmacokinetic methods used for the determination of MRT. Therefore, tools from the theory of linear dynamic syst...

Intercomparisons of hillslopes and catchments in different hydrogeomorphic settings are rare. Those comparison studies that have been completed have focused largely on bulk outflow and chemistry. Here, we present a new functional intercomparison of two well studied hillslopes: one in New Zealand at Maimai and one in Japan at Fudoji. Slope angle, slope length, soil depth, climate and vegetation ...

BACKGROUND Studies from the USA, New Zealand and Denmark suggest that many ethnic minority citizens obtain healthcare in their country of origin. Their reasons for doing so and the possible consequences remain unclear. METHODS We used data from the Healthy Life in an Urban Setting study to investigate the magnitude, types, self-reported reasons and determinants of past-year healthcare consump...

The use of geocoded historical residence as proxy for retrospective assessment of exposure in early life is increasing in epidemiological studies of chronic health outcomes. Dealing with historical residence poses challenges, primarily due to higher uncertainties associated with data collection and processing. A possible source of bias is connected with the exclusion of subjects, who cannot, fo...

The change from depopulation to population increase in the more remote rural areas of England is analyzed using data from a survey of 300 households in North Devon. The heterogeneous nature of the migrants and their reasons for migration are stressed. "The reasons for leaving the former area of residence tended to relate to lifestyle, personal or environmental factors whereas the reasons for ...

Our laboratory is engaged in an ongoing analysis of a 103-compound data set containing reliable intravenous pharmacokinetic parameters in the rat, dog, monkey, and human, and we have previously reported our findings regarding extrapolation of clearance. In this article, we report on our findings regarding volume of distribution and mean residence time. Various allometric and nonallometric metho...

Sequences of residence times (RTs) associated with the escape from metastable states are observed in many fields. Here we study analytically and numerically the correlations among RTs for a bistable stochastic system driven by dichotomous noise. Our theory predicts an oscillatory behavior of the correlations with respect to the lag between RTs. Correlations vanish at all lags if the switching r...

The authors examined the association between perceived safety of neighborhood and likelihood of exercise among adult residents of eight European cities. Data were collected by a survey of neighborhood, housing, and health conducted by the World Health Organization in 2002 and 2003. Baseline category logistic regression models were fit to estimate the association between perceived safety and exe...

based on previous researches and current research indoor contaminations in most of the time were more than outdoor contaminations. in according to, most of our times have been spent in indoor environments (85-90%), therefore, it is necessary to investigate indoor environments. symptoms of sick building syndrome are headache, dizziness, drowsiness. unknown reasons of disease above mentioned and ...

Based on previous researches and current research indoor contaminations in most of the time were more than outdoor contaminations. In according to, most of our times have been spent in indoor environments (85-90%), therefore, it is necessary to investigate indoor environments. Symptoms of sick building syndrome are Headache, dizziness, drowsiness. Unknown reasons of disease above mentioned and ...