the important role of reperfusion therapies in the treatment of acute myocardial infarction is well documented. however, reperfusion therapies can initiate inflammatory response and may damage the myocardium. the purpose of current study was to compare the effects of percutaneous coronary intervention and thrombolytic therapy on inflammatory markers in the setting of st elevation myocardial inf...

results a significant decrease in apoptotic cells and increase in proliferative reaction were observed in the i/r + hbo group compared to the i/r group. conclusions we demonstrated that hbo suppressed apoptosis, which caused inflammation after renal i/r, and promoted tubular cell regeneration. hbo has protective effects against aki caused by renal i/r through the inhibition of apoptosis. materi...

a b s t r a c t introduction: even today there is no effective drug therapy to prevent neuronal loss after brain stroke. in the present study we studied the effect of mitochondrial katp channel regulators on neuronal ultrastructure after ischemia reperfusion in the rat. materials & methods: rats temporarily subjected to four vessels occlusion for 15 minutes followed by 24 hours reperfusion with...

A B S T R A C T Introduction: Even today there is no effective drug therapy to prevent neuronal loss after brain stroke. In the present study we studied the effect of mitochondrial KATP channel regulators on neuronal ultrastructure after ischemia reperfusion in the rat. Materials & Methods: Rats temporarily subjected to four vessels occlusion for 15 minutes followed by 24 hours reperfusion with...

BACKGROUND Treatment with lytics or primary percutaneous coronary interventions (PCI) reduces the mortality rate of patients with ST-elevation myocardial infarction (STEMI) presenting within 12 hours. Patients presenting >12 hours are generally considered to be ineligible for reperfusion therapy, and there are currently no specific treatment recommendations for this subgroup.Methods- All patien...

Background: The main target of treatment STEMI is to restore coronary blood flow and maintain myocardial perfusion. Several tools including electrocardiographic angiographic parameters are used assess reperfusion. Fragmented QRS associated with increased adverse cardiovascular events, it was proved bea marker ventricular dysfunction poor prognosis in STEMI. Aim the work : To study relation betw...

OBJECTIVE To describe the contemporary management and outcomes of patients presenting with ST-segment-elevation myocardial infarction (STEMI) in Australia. DESIGN, PARTICIPANTS AND SETTING Observational analysis of data for patients who presented with suspected STEMI and enrolled in the Australian Acute Coronary Syndrome Prospective Audit from 1 November 2005 to 31 July 2007. MAIN OUTCOME M...

OBJECTIVES. To review the 10-year trend of reperfusion strategies in patients with ST-segment elevation myocardial infarction, and the adoption rate of percutaneous coronary interventions as opposed to thrombolytic therapy. Also to explore why some patients did not receive reperfusion therapy, and document changes in reperfusion strategies after the introduction of primary percutaneous coronary...

Background—There is clear evidence that reperfusion therapy improves survival in selected patients with an acute myocardial infarction. However, several studies have suggested that many patients with an acute myocardial infarction do not receive this therapy. Whether this underutilization occurs in patients appropriate for such therapy remains unclear. Methods and Results—We examined the use of...