نتایج جستجو برای: reperfusion arrhythmia

تعداد نتایج: 55229  

Journal: :iranian biomedical journal 0
babak baharvand mansour esmailidehaj jamileh alihosaini shirin bajoovand saeedeh esmailidehaj zeynab hafizi barjin

background: this study was conducted to reveal that whether i.v. injection of oleuropein, the most potent polyphenolic antioxidant in olive leaf, has any effect on the magnitude of reperfusion arrhythmia in anesthetized rats or not. methods: eighty male wistar rats were divided into 8 groups of 10 each: groups 1 and 5 were assigned as the prophylactic and treatment control groups, groups 2 and ...

Journal: :iranian journal of basic medical sciences 0
moslem najafi department of pharmacology, school of pharmacy and research center for pharmaceutical nanotechnology, tabriz university of medical sciences, tabriz, iran elnaz shaseb school of pharmacy, tabriz university of medical sciences, tabriz, iran saba ghaffary school of pharmacy, tabriz university of medical sciences, tabriz, iran ashraf fakhrju department of pathology, school of medicine, tabriz university of medical sciences, tabriz, iran tahereh eteraf oskouei school of medicine, tabriz university of medical sciences, tabriz, iran

objective(s) in this study, effects of chronic administration of oral natural honey against ischemia/reperfusion (i/r)-  induced cardiac arrhythmias were investigated in isolated rat heart. materials and methods male wistar rats were divided into four groups (n= 10-14 rats in each group) and fed with natural honey (1%, 2% and 4% dissolved in the drinking water) for 45 days except for the contro...

Journal: :iranian journal of basic medical sciences 0
selçuk yaşar abant izzet baysal university, faculty of science and art, biology department 14280 golkoy, bolu turkey ömer bozdoğan abant izzet baysal university, faculty of science and art, biology department 14280 golkoy, bolu turkey salih tunç kaya duzce university, faculty of science and arts, biology department 81620 konuralp, duzce turkey hayriye soytürk orallar abant izzet baysal university, faculty of science and art, biology department 14280 golkoy, bolu turkey

objective(s): electrical inhomogeneity between ischemic and non ischemic myocardium is the basis of arrhythmia which occurs following coronary artery occlusion. the leakage of potassium from the ischemic region to the non ischemic region is very effective in the generation of these arrhythmias. the aim of this study is to research the effect of atp-dependent potassium (katp) channel blocker (gl...

Journal: :the iranian journal of pharmaceutical research 0
alireza garjani ddepartment of pharmacology, faculty of pharmacy, tabriz university of medical sciences, tabriz, iran haleh vaez ddepartment of pharmacology, faculty of pharmacy, tabriz university of medical sciences, tabriz, iran. abbas delazar drug applied research center, tabriz university of medical sciences, tabriz, iran maryam rameshrad ddepartment of pharmacology, faculty of pharmacy, tabriz university of medical sciences, tabriz, iran fariba heshmatiafshar department of pharmacognosy, faculty of pharmacy, tabriz university of medical sciences, tabriz, iran. parina asgharian student research committee, faculty of pharmacy, tabriz university of medical sciences, tabriz, iran.

myocardial infarction is a common presentation of coronary artery disease and the leading cause of death worldwide. the present study was investigated potential resistance to ischemia-reperfusion (i/r) injuries following administration of methanolic (meoh) extract of scrophularia frigida (s. frigida) in isolated rat heart. male wistar rat hearts (n= 8-10) were isolated and allowed to equilibrat...

Journal: :physiology and pharmacology 0
fatemeh safari dept of physiology, faculty of medical sciences, tarbiat modares university, tehran sohrab hajizadeh dept of physiology, faculty of medical sciences, tarbiat modares university, tehran shahnaz shekarforush islamic azad university, arsanjan branch, fars mehdi forouzandeh dept. medical biotechnology, faculty of medical sciences, tarbiat modares university, tehran, iran mohsen foadoddini department of physiology and pharmacology, birjand university of medical sciences, birjand, iran gholamreza bayat dept of physiology, faculty of medical sciences, tarbiat modares university, tehran

introduction: inhibition of renin angiotensin system represents an important approach in the management of cardiovascular diseases. the aim of this study was to explore the effects of pretreatment with non-hypotensive dose of angiotensin converting enzyme (ace) inhibitor, ramiprilat and angiotensin type 1 (at1) receptor blocker, losartan on myocardial infarct size and arrhythmias in a rat model...

Journal: :iranian journal of basic medical sciences 0
moslem najafi department of pharmacology, school of pharmacy, research center for pharmaceutical nanotechnology, tabriz university of medical sciences, tabriz, iran saba ghaffary department of pharmacology, school of pharmacy, tabriz university of medical sciences, tabriz, iran elnaz shaseb department of pharmacology, school of pharmacy, tabriz university of medical sciences, tabriz, iran

objective(s) this study aimed to examine whether acetyl-l-carnitine (alc) was able to reduce cardiac arrhythmias and infarct size in the ischemic-reperfused isolated rat heart. materials and methods the isolated hearts were mounted on a langendorff apparatus then perfused by a modified krebs-henseleit solution during 30 min regional ischemia and 120 min reperfusion (control) or by enriched kreb...

Journal: :iranian journal of basic medical sciences 0
moslem najafi department of pharmacology, school of pharmacy, drug applied research center and research center for pharmaceutical nanotechnology, tabriz university of medical sciences, tabriz, iran elham ghasemian department of pharmacology, school of pharmacy, tabriz university of medical sciences, tabriz, iran fatemeh fathiazad department of pharmacognosy, school of pharmacy, tabriz university of medical sciences, tabriz, iran alireza garjani research center for pharmaceutical nanotechnology, tabriz university of medical sciences, tabriz, iran

objective(s) dracocephalum moldavica (d. moldavica) have been traditionally used as a cardiotonic agent in the folk medicine of some regions of iran. in the present study, effects of total extract of d. moldavica on ischemia/reperfusion induced arrhythmias and infarct size investigated in isolated rat heart. materials and methods the isolated hearts were mounted on a langendorff apparatus then ...

Journal: :journal of sleep sciences 0
zohreh edalatyzadeh department of physiology, school of medicine, tehran university of medical sciences, tehran, iran alireza imani department of physiology, school of medicine, tehran university of medical sciences, tehran, iran mahdieh faghihi department of physiology, school of medicine, tehran university of medical sciences, tehran, iran samira choopani department of physiology, school of medicine, tehran university of medical sciences, tehran, iran sahar askari department of physiology, school of medicine, tehran university of medical sciences, tehran, iran marjan aghajani department of physiology, school of medicine, tehran university of medical sciences, tehran, iran

background and objective : sleep deprivation (sd) is caused by a host of reasons and has numerous consequences on cardiac system. in this study, we aimed to assess the preconditioning effects of acute sd on ischemia (is)-induced ventricular arrhythmias in isolated rat hearts. materials and methods : male wistar rats randomly were placed into the four groups: is-group, acute sd group, control gr...

Journal: :iranian journal of pharmaceutical research 0
moslem najafi school of pharmacy, tabriz university of medical sciences, tabriz, iran mahsa haghighat azari student research committee, faculty of pharmacy, tabriz university of medical sciences, tabriz, iran

in the current study, effects of acute short term administration of fructose on cardiac arrhythmias and myocardial infarction size following ischemia/reperfusion were investigated in isolated rat heart. the hearts were subjected to 30 min zero flow global ischemia followed by 120 min reperfusion. in the control group, the hearts were perfused by normal drug free krebs-henseleit (k/h) solution t...

Journal: :Circulation 1990
T Miura

While coronary thrombolytic therapy in clinical practice is well established for acute myocardial infarction, the injury associated with reperfusion ("reperfusion injury") is still under intense investigation regarding its nature and the strategy for its prevention. Reperfusion injury has been defined as cell injury caused by reperfusion itself, in contradistinction to cell injury caused by the...

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