background: intravenous immunoglobulin (ivig) is an established treatment of immune mediated demyelinating neuropathy including guillain-barré syndrome and chronic inflammatory demyelinating polyneuropathy. recent trials suggest its efficacy in treating relapsing- remitting multiple sclerosis. ivig exerts a number of effects, which may be beneficial in treating multiple sclerosis (ms): reductio...

results of all the ms patients, 78 (95.1%) and 21 (25.6%) were positive for anti-vzv and vzv dna, respectively. statistical analysis of the pcr results showed a significant correlation between the abundance of vzv and ms disease (p < 0.001). however, there was no significant correlation between the abundance of anti-vzv antibodies and ms disease by the elisa method. conclusions these results su...

background: intravenous immunoglobulin (ivig) is an established treatment of immune mediated demyelinating neuropathy including guillain-barré syndrome and chronic inflammatory demyelinating polyneuropathy. recent trials suggest its efficacy in treating relapsing- remitting multiple sclerosis. ivig exerts a number of effects, which may be beneficial in treating multiple sclerosis (ms): reductio...

background:  multiple  sclerosis  (ms) is a  chronic inflammatory  demyelinating  and  neurodegenerative disease  of central  nervous  system  with unknown  causes. etiology of ms involves  both  genetic  and  environment factors.  the  interleukin  7   receptor   (il7r)   gene   is  a promising candidate  for ms, because its involvement in the autoimmunity, regulation of the t-cell homeostasis...

results when the two ms groups were compared together, we found that cr was significantly increased (p value=0.008) and naa/cr was significantly decreased (p value=0.03) in non-enhancing lesions in ppms compared with rrms. there was no significant difference in naa, cho or naa/cho between the two ms subtypes. conclusion mrs is a potential way to differentiate ppms and rrms. objectives we compar...

background: we compared bone mineral density (bmd) in patients with relapsing-remitting multiple sclerosis (rrms) on interferon with that of patients with relapsing-remitting multiple sclerosis (rrms) who were not receiving interferon and healthy age- and sex-matched controls. methods: overall, 30 patients with rrms on interferon (treated patients), 30 patients with rrms but not receiving inter...

background: optical coherence tomography (oct) is a simple, high-resolution technique to quantify the thickness of retinal nerve fiber layer (rnfl) and macula volume, which provide an indirect measurement of axonal damage in multiple sclerosis (ms). this study aimed to evaluate oct finding in relapsing-remitting ms patients of the northwest of iran and compare them with a normal control group. ...

#### Notable in Neurology This Week This issue features an article that investigates the safety of ocrelizumab people with relapsing and primary progressive multiple sclerosis; another examines whether a computer deep learning algorithm can detect MRI-negative focal cortical dysplasia. A featured Review neurologic conditions seen vaccines, including mRNA adenovirus vector coronavirus disease 2...

The Oslo Multiple Sclerosis (MS) Registry was established in 1990, and this is the first report on the prevalence and incidence of MS in the city of Oslo, Norway. The prevalence rate of definite MS on 1 January 1995 was 120.4/10(5). Inclusion of patients of native Norwegian ancestry only and exclusion of non-Norwegian immigrants yielded a prevalence rate of 136.0/10(5). A similar prevalence rat...

With disease-modifying treatments available for relapsing-remitting multiple sclerosis (MS), the quest for therapies for progressive MS has become a key focus of research.