objective(s): regulatory t cells, including cd4+cd25+fox3+ and cd8+cd28- cells play an important role in regulating the balance between immunity and tolerance. since multiple sclerosis is an inflammatory autoimmune disease, regulatory t cells are considered to be involved in its pathogenesis. in this study, we investigated the circulatory numbers of the two mentioned types of regulatory t cells...

background: it is now well-demonstrated that histone demethylases play an important role in developmental controls, cell-fate decisions, and a variety of diseases such as cancer. lysine-specific demethylase 5d (kdm5d) is a male-specific histone demethylase that specifically demethylates di- and tri-methyl h3k4 at the start site of active genes. in this light, the aim of this study was to invest...

helicobacter pylori (h. pylori) is a gram-negative bacterium that colonizes the human stomach and affects more than half of the global human population. this microorganism shows variations in its geographical distribution and causes chronic gastritis, peptic ulcer, gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. the development of these clinical entities depends on the ba...

soluble forms of nonclassical human leukocyte antigen (hla)-g have recently been suggested as immunomodulatory factors in multiple sclerosis (ms). hla-g inhibits the effecter function of t cells and natural killer (nk) cells. also regulatory t cells (treg) are considered as pivotal players in ms pathogenesis. thus, we aimed to evaluate the presence of hla-g molecules and treg cells in relapsing...

In this paper Basel regulation is modeled in Dynamic Stochastic General Equilibrium (DSGE) framework. For this purpose, using data from 1981-2017 for Iran, capital adequacy as an importance regulation is modeled. Results show Basel regulation has procyclical effect. According to the results of the model and according to the realities of economy and banking system of Iran, in recession, lending ...

t regulatory cells play a crucial role in immunological unresponsiveness to self- antigens and in suppressing excessive immune responses deleterious to the host. t regulatory cells are produced in the thymus as a functionally mature subpopulation of t cells. they can be induced from naive t cells in the periphery and express their marker as a forkhead/winged helix transcription factor called fo...

the present study aimed to explore (a) if there is any relationship between efl teachers’ self-regulatory and their resiliency, (b) if there is any relationship between efl teachers’ self-regulatory and their genders, and (c) if there is any relationship between efl teachers’ self-regulatory and years of teaching experience. through a convenience method of sampling, the first group of participa...

conclusions based on the presence of ta systems in the majority of p. aeruginosa isolates, these could be used as a novel target for antimicrobial therapy. results our results showed that in the 174 p. aeruginosa isolates, relbe and higba were universal, but parde was less prevalent. both of the flanking regions of the parde genes in all positive isolates were amplified. the flanking regions of...

background & aim: investigation of suspension cell culture and callus production in catharanthus roseus. catharanthus roseus is an herbaceous perennial plant belongs to the family apocynaceae. c. roseus is important as commercial medicinal plant because of its alkaloidal content. whole plant contains about 130 alkaloids those are classified as vinca alkaloids. vincristine and vinblastine; t...

The sulfur regulatory circuit of the filamentous fungus, Neurospora crassa, consists of a set of unlinked structural genes which encode sulfur catabolic and two major regulatory genes which govern their expression. The cys-3 regulatory gene encode a transacting regulatory protein which activates the expression of cys-14 and ars, whereas the other regulatory genes Scon-l and Scon-2 appear to...