purpose: to evaluate the effect of intravitreal triamcinolone acetonide (ivt) reinjection on clinical and optical coherence tomographic (oct) features in refractory diabetic macular edema (dme). methods: in an interventional case series, all ivt-treated patients enrolled in a previous clinical trial (45 subjects), were recalled for performing a new ophthalmologic examination and oct. suitable e...

purpose: to evaluate the effect of intravitreal triamcinolone acetonide (ivt) on clinical, angiographic, and optical coherence tomographic parameters in refractory diabetic macular edema (dme). methods: in a double-masked placebo-controlled randomized clinical trial, 88 eyes of 61 patients with dme refractory to previous laser therapy or not suitable for such treatment were included in the stud...

purpose: to evaluate the influence of different confounding factors on the effect of intravitreal triamcinolone acetonide injection for refractory diabetic macular edema. methods: in a prospective placebo-controlled randomized clinical trial, 88 eyes with refractory diabetic macular edema were randomly assigned into two groups including 45 in the treatment group (4 mg intravitreal triamcinolone...

purpose : to compare the 6-months anatomic and best corrected visual acuity (bcva) responses after primary intravitreal bevacizumab (ivb intravitreal avastin) and ivb plus macular photocoagulation (mpc) in diabetics with clinically significant macular edema (csme) methods : in this interventional randomized clinical trial (rct) 40 diabetics (80 eyes) with bilateral csme and non-proliferative di...

BACKGROUND Kidney failure provoked by glomerulosclerosis leads to fluid filtration deficits and other disorders of kidney function. Refractory diabetic macular edema (DME) can be another warning sign of glomerulosclerosis in diabetic patients. CASE A 40-year-old Saudi male presented with macular edema that was refractory to all possible medical and surgical ophthalmic interventions in both ey...

Diabetic macular edema (DME) is arguably one of the most important challenges in ophthalmology. Macular edema refractory to laser photocoagulation remains the most prevalent cause of untreatable vision loss in diabetes and is responsible for visual disability in millions of people worldwide. The lack of an effective therapeutic solution accounts for the range of interventions proposed. These in...

purpose: to evaluate the anatomic and visual results and complications of vitrectomy in eyes with diffuse refractory diabetic macular edema associated with a taut posterior hyaloid. methods: this prospective interventional case series was conducted on 25 eyes of 22 patients with diffuse clinically significant diabetic macular edema, macular thickness greater than 250 microns on optic coherence ...

PURPOSE Diabetic macular edema can be refractory to multiple treatment modalities. Although there have been anecdotal reports of ranibizumab showing efficacy when other modalities provided limited benefit, little has been published on treatment for refractory diabetic macular edema. This study sought to investigate this observation further. METHODS Retrospective chart review. RESULTS Thirty...

macular edema following diabetic retinopathy is one of the ocular complications associated with diabetes, and it is the leading cause of visual loss in the active young and middle aged population in developed countries. while all patients with diabetes particularly those with diabetic retinopathy are at increased risk of developing eye complications, early detection and timely intervention may ...

purpose: to determine if intravitreal injection of triamcinolone acetonide is safe and effective in the treatment of diabetic macular edema unresponsive to prior laser photocoagulation. methods: fifty-four eyes of 38 patients with clinically significant macular edema which had received at least two sessions of laser photocoagulation according to early treatment diabetic retinopathy study guidel...