Electromagnetic waves affect living organisms and it is of great interest for wide interaction of new sources with a diversity of frequencies and powers to life of people. In the last few years, many authors have proposed that the biological effect of electromagnetic fields in both the high-frequency and low-frequency ranges are connected with oxidative processes in tissues. Studying the change...

Electromagnetic waves affect living organisms and it is of great interest for wide interaction of new sources with a diversity of frequencies and powers to life of people. In the last few years, many authors have proposed that the biological effect of electromagnetic fields in both the high-frequency and low-frequency ranges are connected with oxidative processes in tissues. Studying the change...

Tissue redox status is one of the most important parameters to maintain homeostasis in the living body. Numerous redox reactions are involved in metabolic processes, such as energy production in the mitochondrial electron transfer system. A variety of intracellular molecules such as reactive oxygen species, glutathione, thioredoxins, NADPH, flavins, and ascorbic acid may contribute to the overa...

A widely accepted hypothesis indicates that the accumulation of oxidative damage arising from endogenously produced reactive oxygen species (ROS) is one of the main triggers of cellular senescence, agerelated disorders and cancer development. High ROS levels are responsible for lipid peroxidation, protein, and DNA oxidation, thus seriously threatening cellular fate and enhancing mutations risks...

Using Arabidopsis plants Col-0 and vtc2 transformed with a redox sensitive green fluorescent protein, (c-roGFP) and (m-roGFP), we investigated the effects of a progressive water stress and re-watering on the redox status of the cytosol and the mitochondria. Our results establish that water stress affects redox status differently in these two compartments, depending on phenotype and leaf age, fu...

Maintenance of a reducing redox balance is a critical physiologic function of red cells (RBC) that can be perturbed in variety of RBC pathologies. Here we describe a new approach to evaluate in vivo RBC redox status using a redox sensitive GFP (roGFP2) sensor under control of a β-globin mini-promoter, directing expression specifically to erythroid cells. RoGFP2 expressing RBCs demonstrate ratio...

The purpose of this study was to noninvasively monitor tumor oxygenation and redox status during hyperoxygenation treatment, such as carbogen-breathing, in a murine tumor model using in vivo electron paramagnetic resonance (EPR) spectroscopy and imaging techniques. The study was performed using implanted lithium phthalocyanine (LiPc) microcrystals as the oximetry probe and 3-carbamoylproxyl (3-...

BACKGROUND Few strains have been found to produce isobutanol naturally. For building a high performance isobutanol-producing strain, rebalancing redox status of the cell was very crucial through systematic investigation of redox cofactors metabolism. Then, the metabolic model provided a powerful tool for the rational modulation of the redox status. RESULTS Firstly, a starting isobutanol-produ...

Hepatic fibrosis is a chronic disorder caused by viral infection and/or metabolic, genetic and cholestatic disorders. A noninvasive procedure that enables the detection of liver fibrosis based on redox status would be useful for disease identification and monitoring, and the development of treatments. However, an appropriate technique has not been reported. This study describes a novel method f...