sickle cell disease is a genetic haemoglobinopathy with consequent haemolysis and anaemia. it is of interest to study its effect on red cell indices beside haemoglobin concentration.the objective of the study is to determine the values of red cell indices in preschool-age children with sickle cell anaemia.we conducted a cross-sectional study including 97 children with sickle cell anaemia aged s...

Background: Erythrocytes require an ability to deform and to withstand shear stress while negotiating the microcirculation. These properties are largely due to their excess surface area per volume and the characteristics of the membrane’s protein. Deficiencies of these proteins are associated with chronic haemolysis. Methods: This was a cross sectional  study aimed at determining the prevalenc...

A high prevalence of iron deficiency was found in apparently healthy Asian immigrant children in Harrow. After excluding children with overtly abnormal red cell indices, Asian and European children had identical haemoglobin values, but Asian children had much lower mean cell volume and mean corpuscular haemoglobin values and higher red blood cell values.

BACKGROUND The red cell indices quantify the size, number and oxygen-carrying ability of erythrocytes. Although the genetic basis of many monogenic forms of anaemia is well understood, comparatively little is known about the genes responsible for variation in the red cell indices among healthy participants. OBJECTIVE To identify quantitative trait loci (QTLs) responsible for normal variation ...

BACKGROUND Sickle cell disease is a genetic haemoglobinopathy with consequent haemolysis and anaemia. It is of interest to study its effect on red cell indices beside haemoglobin concentration. OBJECTIVES The objective of the study is to determine the values of red cell indices in preschool-age children with sickle cell anaemia. METHODS we conducted a cross-sectional study including 97 chil...

Background: This study was undertaken to see the utility of erythrocyte indices for screening of beta thalassemia trait in pregnant women, as these indices are based on complete blood count reports which are routinely available and nowadays generated by automated hematology analyzer. Material and methods: The study was a cross sectional in which the complete blood count report of 300 pregnant w...

Anaemia is defi ned by the haemoglobin concentration in peripheral blood being below the normal 14 gm/dL (SD ± 2) for women, 16 gm/dL (SD ± 2) for men and 12 gm/dL (SD ± 2) for children. The number of red blood cells is also usually reduced, below the normal 4.8 × 10/mm (SD ± 0.6) for women and 5.4 × 10/mm (SD ± 0.9) for men. The haematocrit is the proportion of red blood cells in the blood – n...