sickle cell disease is a genetic haemoglobinopathy with consequent haemolysis and anaemia. it is of interest to study its effect on red cell indices beside haemoglobin concentration.the objective of the study is to determine the values of red cell indices in preschool-age children with sickle cell anaemia.we conducted a cross-sectional study including 97 children with sickle cell anaemia aged s...

a total of 1695 blood samples collected from ten ethnically distinct populations of iran (turks and kurds of rezaieh, lurs, aabolis, baluchis, turks and kurds of shrvan, zoroastrians, tehranis, and kermanis) were examined for six polymorphic red cell enzyme systems, namely red cell acid phosphatase (ap), adenylate kinase (ak), phosphoglucomutase (pgm1), esteraxe d (esd), adenosine deaminase (ad...

introduction although thymoma is the most common anterior mediastinal tumor, only 5% of thymoma cases develop pure red cell aplasia (prca). case presentation in this article we have reported a 59-year-old man with a large anterior mediastinal mass (diameter of 10 cm) and severe anemia, that thymoma and pure red cell aplasia have been demonstrated by histopathologic and hematological examination...

background: to investigate the association between the red cell distribution width (rdw) and mortality in patients with acute pancreatitis (ap), and to assess the ability of rdw to predict mortality in ap patients. materials and methods: this retrospective cohort study included 120 patients (50 males and 70 females) with ap who were admitted to the first affiliated hospital of zhongshan medical...

although the most common hematological disturbance in thymoma is pure red cell aplasia, pancytopenia is a very rare paraneoplastic syndrome in this disorder. we only found one case in literature reviews. we report a 36 year old female with an anterior mediastinal mass and severe pancytopenia. with a mediastinotomy incision, biopsy of the tumor was obtained. the report of the pathologist was thy...

background: asphyxia is a common cause of perinatal mortality in 5-10% of all births worldwide. the present parameters for determining perinatal asphyxia, e.g. preeclampsia, cannot be considered as markers per se, and require auxiliary markers, e.g. increased number of nucleated red blood (nrbc) cells, for early diagnosis of perinatal asphyxia. objective: in this study, we evaluated the mean nr...

linezolid (lzd), severed as the first oxazolidinone antibiotic, was active against multidrug-resistant gram-positive strains. lzd can induce thrombocytopenia, anemia and leukocytopenia. currently, reports on pure red cell aplasia (prca) cases induced by lzd are relatively rare [4-7]. in this paper, we reported a patient with prca twice induced by lzd. a 37-year-old man was diagnosed with myelody...

there is evidence indicating that pomegranate juice contains many of the essential properties necessary to retain cell viability and cell proliferation. these properties indicate that pomegranate juice is a suitable storage medium for avulsed teeth. however, this idea has not yet been tested. in this study, the capacity of pomegranate juice (pj) as a storage medium for retaining avulsed teeth w...

the aim of this study was to compare invasive and non-invasive strains of shigella flexneri isolated from tehran by a 120 kda protein band by sds-page, electron microscopy of cell culture and congo red dye methods. methods: s. flexneri strains were isolated by standard bacterial methods from fecal specimens of children attending to the 3 children’s hospitals. phenotype analysis for screening vi...

the pharmacokinetics of recombinant human erythropoietin (rhuepo) administered intravenously has been investigated in a group of five patients with chronic renal failure who were dialysis-dependent. the half-life of circulating erythropoietin decreased from 7.9±oa hr (mean ±so) at the beginning of treatment to 6.2±o.6 hr after 6 weeks and 5a±o.9 hr after 4 months of treatment. in spite of the s...