introduction and aims: in order to prevent liver cirrhosis and hepatocellular carcinoma in later life, it is essential to prevent hepatitis b virus (hbv) infection in infants. despite the availability of an effective vaccine, hepatitis b still continues to be a significant health problem. the aim of this study is to reveal the efficacy of passive and active immunoprophylaxis for preventing peri...

In order to determine the efficacy of recombinant hepatitis B vaccine in Iranian infants, we analyzed the efficacy of a recombinant hepatitis B vaccine in 115 infants aged 12-24 months born to HBsAg negative mothers who received three doses of HBV Antibody to hepatitis B surface antigen (anti-HBs) was checked after the third dose of the vaccine, 94.8% of the infants had developed protective...

in order to determine the efficacy of recombinant hepatitis b vaccine in iranian infants, we analyzed the efficacy of a recombinant hepatitis b vaccine in 115 infants aged 12-24 months born to hbsag negative mothers who received three doses of hbv antibody to hepatitis b surface antigen (anti-hbs) was checked after the third dose of the vaccine, 94.8% of the infants had developed protective ant...

objective: preventing communicable diseases in the armed forces (af) of a country is considered as a national interest and has a great importance. there are limited data on the efficacy of vaccination of the navy personnel. this study was designed to evaluate both the safety and the immunogenicity of a recombinant hepatitis b (hb) vaccine made by pasteur institute of iran (ipi-rhb), in this tar...

background: 1.3% of people in iran are positive for anti-hbc antibody.the objective of this study is to determine the rate of seroconversion in those with persistent isolated anti-hbc after vaccination. materials and methods: in a quasi-experimental study, 94 persons with isolated anti-hbc antibody who were referred to tehran blood transfusion organization between 2002 and 2004 were selected th...

long-term protection against hepatitis b virus (hbv) is dependent on persistence of anti-hbs antibodies and/or strong immunological memory. in this study we evaluated the persistence of anti-hbs antibodies in healthy iranian children 5 years after primary vaccination and the response to a booster dose using recombinant hepatitis b vaccine. totally, 81 children who had received primary course of...

OBJECTIVE To evaluate the effects of hepatitis B vaccine and immunoglobulin in newborn infants of mothers positive for hepatitis B surface antigen. DESIGN Systematic review and meta-analysis of randomised clinical trials. DATA SOURCES Electronic databases and hand searches. REVIEW METHODS Randomised clinical trials were assessed for methodological quality. Meta-analysis was undertaken on ...

The plasma derived vaccine for hepatitis B became commercially available in 1982 but its availability was limited. The new generation of hepatitis B vaccine (recombinant rDNA yeast derived) can be produced in greater quantities at a comparable cost. Recombinant HBV vaccine given in infancy is highly immunogenic. Most infants develop antibody titre well above 10 m1U/ml, the level associated with...

Background & Aims: Hepatitis B virus is one of the causes of acute and chronic hepatitis. Due to multiple hospitalization and blood transfusion, thalassaemic patients are at higher risk of this infection. Duration of the immunity after vaccination in this high-risk group and the need for booster vaccination is uncertain. The aim of this study was to find antibody titration and immunity to Hepat...