inhibitor development is a lifelong challenge for patients with bleeding disorders who received replacement therapy. most commonly, inhibitor formation was observed in hemophilia a patients but patients with rare bleeding disorders (rbd) especially patients with deficiency of factor xiii (fxiii) and factor v (fv) can develop an inhibitor against exogenous factors. several factors considered as ...

abstract malacoplakia is a rare chronic inflammatory disease associated with infection and immunosuppression, and very few occurrences have been reported in the bone. the authors describe the case of a 22-year-old woman with paraplegia and urinary and fecal incontinence whose thoracic spine magnetic resonance imaging suggested a tumoral or extensive inflammatory process in the body of the 8th, ...

using the gaussian 2003 software and mp2/ 6–311 ++ g** method for he: he, ne:ne andmp2/6-31g method for ar: ar, kr: kr and hf/sto-3g method for xe: xe, the optimizedinteraction energies between two like atoms of rare gases (he, ne, ar, kr and xe) as a functionof the distances between the centers of two considered atoms were evaluated and the resultswere interpreted according to the lennard – jo...

introduction: neonatal nasal airway obstruction induces various degrees of respiratory distress. the management of this disease, including surgical repair, will depend on the severity and location of the obstruction. we describe here a case of congenital nasal nostril stenosis that required surgical repair for stenting of both nares after coanal atresia repair.   case report: a 2 days old femal...

an accurate diagnosis of the morphology of the root canal system is a pre-requisite for successful root canal treatment. frequently, root canals are left untreated because the clinicians fail to identify their presence, particularly in teeth that have anatomical variations or additional root canals. in this report a maxillary lateral incisor with two roots has been described.

factor v (fv) deficiency is a rare bleeding disorder (rbd) that inherit in autosomal recessive manner. diagnosis of fv deficiency (fvd) is made by routine coagulation tests, fv activity and molecular analysis. in patients with fvd, routine coagulation tests including activated partial thromboplastin time (aptt), prothrombin time (pt) and evenbleeding time (bt) are prolongedwhile thrombin time (...

background: the appearance of multi-drug resistant microorganisms is becoming a global problem. already several strategies have been employed for overcoming antibiotic resistance issue. developing new antimicrobial compounds from microbial source could be a beneficial solution. hence screening programs in order to discover new antibiotics from microbial entities is interesting. because of high ...