نتایج جستجو برای: ranging consequences

تعداد نتایج: 269987  

Introduction: Corruption is one of the major obstacles to achieving progress and development in the communities and countries. Hence, understanding the phenomenon of corruption, types, and measurement parameters and negative consequences of corruption in various aspects of political, administrative, social, and economic fields may help strategies to fight with corruption. Therefore, the aim of ...

Introduction: Chronic low back pain is a complex disorder with wide-ranging adverse consequences that can impact on people’s lifestyles. It has been suggested that further research is needed to develop a better understandin[1]g of its impact  and helped reaserchers to develop and adapt multicomponent interventions that will address patients needs. Thus,The purpose of this study was to examine ...

Journal: :TRANSACTIONS OF THE JAPAN SOCIETY FOR AERONAUTICAL AND SPACE SCIENCES, AEROSPACE TECHNOLOGY JAPAN 2014

2017
Indranil Malik Chenxi Qiu Thomas Snavely Craig D. Kaplan

Here we employ a set of RNA Polymerase II (Pol II) activity mutants to determine the consequences of increased or decreased Pol II catalysis on gene expression in Saccharomyces cerevisiae. We find that alteration of Pol II catalytic rate, either fast or slow, leads to decreased Pol II occupancy and apparent reduction in elongation rate in vivo. However, we also find that determination of elonga...

Journal: :Journal of the Franklin Institute 1920

2016
Débora de Paula Michelatto Leif Karlsson Ana Letícia Gori Lusa Camila D'Almeida Mgnani Silva Linus Joakim Östberg Bengt Persson Gil Guerra-Júnior Sofia Helena Valente de Lemos-Marini Michela Barbaro Maricilda Palandi de Mello Svetlana Lajic

We present the functional and structural effects of seven novel (p.Leu12Met, p.Arg16Cys, p.Ser101Asn, p.Ser202Gly, p.Pro267Leu, p.Gln389_Ala391del, and p.Thr450Met) and two previously reported but not studied (p.Ser113Phe and p.Thr450Pro) CYP21A2 mutations. Functional analyses were complemented with in silico prediction of mutation pathogenicity based on the recently crystallized human CYP21A2 ...

Journal: :Biology letters 2014
Samantha C Patrick Henri Weimerskirch

Specialists and generalists often coexist within a single population, but the biological drivers of individual strategies are not fully resolved. When sexes differ in their foraging strategy, this can lead them to different environmental conditions and stability across their habitat range. As such, sexual segregation, combined with dominance, may lead to varying levels of specialization between...

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