aptamers, or single stranded oligonucleotides, are produced by systematic evolution of ligands by exponential enrichment, abbreviated as selex. in the amplification and regeneration step of selex technique, dsdna is conversed to ssdna. asymmetric pcr is one of the methods used for the generation of ssdna. the purpose of this study was to design a random dna library for selection of aptamers wit...

a random 12 mers phage library was used to screen a pool of immunoglo¬bulin fractions obtained from vitiligo patients. subsequent to panning experiments, a panel of affinity selected phage from vitiligo patients were obtained. this panel was tested using an elis a for their reactivity with pooled sera from patients and normal controls. among the 16 randomly selected clones, two of clones showed...

Significance The structure of life emerged from randomness. This is attributed to selection by molecular Darwinian evolution. study found that random templated ligation led the simultaneous elongation and sequence oligomers. Product strands showed highly structured motifs which inhibited self-folding built self-templating reaction networks. By reduction space, kinetics duplex formation increase...

Rapid loss of global biodiversity has motivated a number of recent experiments that seek to understand how species richness affects ecosystem functioning. In the first round of studies, researchers have formed local communities differing in richness by selecting species at random from an experimental species pool, which is a subset of the 'regional' collection of species. Often, the effects of ...

The collective motion of bacterial cells in a shallow circular pool is systematically studied using the bacterial species Bacillus subtilis. The ratio of cell length to pool diameter (i.e., the reduced cell length) ranges from 0.06 to 0.43 in our experiments. Bacterial cells in a circular pool show various types of collective motion depending on the cell density in the pool and the reduced cell...

The objective of this study was to investigate the possibility of a generic rating curve with a small number of adjustable parameters for the restricted class of bedrock step-pool rivers. The motivation for this study arose from Utah Valley University’s long-term program of groundwater development in the Trans-Mexican Volcanic Belt, which requires hydrographs for bedrock step-pool rivers near r...