UNLABELLED The purpose of this investigation was to develop and evaluate a new and rapid miniaturized chromatography system that would accurately assess the radiochemical purity of 99mTc-tetrofosmin without the problems of solvent ratios and time requirements associated with the manufacturer's recommended procedure. METHODS The migration of the radiochemical components of 99mTc-tetrofosmin wa...

Chromatographic quality control testing of radioiodinated monoclonal antibodies (WJ MOAB) is necessary to assess radiochemical purity prior to patient injection. Conventional gel exclusion chromatography column scanning (GCS) is time consuming and not practical. We investigated rapid miniaturized chromatographic procedures for evaluating the radiochemical purity of 1311 MOAB. Three systems were...

This report describes the methods and procedures used by the U.S. Geological Survey Tritium Laboratory to analyze natural waters for tritium activity. Samples having low activity are electrolytically enriched in cells with nickel and steel electrodes, and their tritium concentration is subsequently determined by liquid scintillation and gas phase counting techniques. Samples having high tritium...

Radioactive waste generated in decommissioning activities need be classified according to their radioactive content. The radiological information required by national authorities includes diverse alpha and beta emitters, which can only be determined after a radiochemical separation process. This paper presents the work on the development of radiochemical methods for the simultaneous separation ...

Good radiochemical purity of hippuran is important regarding the patient's radiation dose, primarily because of the high thyroid exposure from free iodide. The radiochemical purity and in vitro stability of 11 commercially available 131I, 125I, and 123I hippurans were analyzed by means of thin layer chromatography. Three different radioactive impurities were found in all hippuran samples: (a) f...