background: quantification of radiation-induced apoptosis in peripheral blood lymphocytes (pbls) has been proposed as a possible screening test for cancer-prone individuals and also for the prediction of normal tissue responses after radiotherapy. materials and methods: the neutral version of the comet assay (single-cell gel electrophoresis) was used 24, 48, 72 hours after irradiation with 8 gy...

Background: Quantification of radiation-induced apoptosis in peripheral blood lymphocytes (PBLs) has been proposed as a possible screening test for cancer-prone individuals and also for the prediction of normal tissue responses after radiotherapy. Materials and Methods: The neutral version of the comet assay (single-cell gel electrophoresis) was used 24, 48, 72 hours after irradiation ...

oral glutamine supplementation is highly effective in preventing and delaying radiation-induced esophagitis, one of the most common discomforting side effects of radiation to the thoracic area among lung cancer patients. according to the literature, lung cancer is the leading cause of death among all cancers with the highest incidence worldwide. this paper aims to emphasize the importance of or...

Introduction: The present study aimed to measure the scatter and leakage dose received by out-of-field organs while delivering Radiotherapy (RT) treatment of cervical cancer. Moreover, this study estimated the risk of second cancer (SC). The doses to out-of-field organs were measured using a lithium fluoride (TLD 100) dosimeter while delivering External Beam Radiothera...

the aim of this study was to investigate the radioprotective effect of thymol as a natural product against salivary glands dysfunction induced by ionizing radiation in rats. the rats were treated with thymol at dose of 50 mg/kg before exposure to radiation at dose 15gy. salivary gland function was evaluated with radioisotope scintigraphy and then salivary gland to background counts ratio was ca...

background: radiation-induced lung toxicity is an important dose-limiting toxicity in lung cancer radiotherapy, for which there are no generally accepted predictive factors. this study seeks to identify risk factors associated with the development of severe radiation-induced lung toxicity using clinical and dosimetric parameters. methods: we reviewed the medical records of 54 patients with hist...

objective: cervical cancer is the second most common cause of death from cancer in women throughout the world. the aim of this study was to evaluate the cytotoxic activity of kelussia odoratissima (k. odoratissima) extract associated with radiotherapy in cervical cancer cells (hela cell line).materials and methods: different concentration of the extract (25-500µg/ml) was tested in hela cell lin...

malignant tumors of head and neck carcinomas are the sixth most common type of cancer. current systemic therapies for cancer show side effects in normal tissues and short-term efficacy due to drug resistance. consequently, there is much interest in identifying new drugs for cancer treatment. crocin (an active ingredient of saffron) has been shown to have cytotoxic effects on cancer cell lines. ...

Malignant tumors of head and neck carcinomas are the sixth most common type of cancer. Current systemic therapies for cancer show side effects in normal tissues and short-term efficacy due to drug resistance. Consequently, there is much interest in identifying new drugs for cancer treatment. Crocin (an active ingredient of saffron) has been shown to have cytotoxic effects on cancer cell lines. ...