purpose: to evaluate the role of active uveitis on refractive errors changes. methods: a cohort single group study was conducted on patients with acute or recurrent uveitis. cyclorefraction was performed in both phases of active and quiescent. sphere, cylinder and sphere equivalent power were compared in active and quiescent phases and analyzed statistically. results: sixty-six patients (eighty...

PURPOSE To test the association between elevated proportions of CD1c+ myeloid dendritic cells (mDCs) and disease activation/reactivation in noninfectious uveitis. METHODS Noninfectious uveitis patients (n = 89) and healthy controls (n = 111) were recruited. The proportion of CD1c+ mDCs in the total dendritic cell (DC) population of peripheral blood was measured by flow cytometry (CD1c+ mDCs g...

IMPORTANCE Uveitic glaucoma is among the most common causes of irreversible visual loss in uveitis. However, glaucoma detection can be obscured by inflammatory changes. OBJECTIVE To determine whether retinal nerve fiber layer (RNFL) measurement can be used to detect glaucoma in uveitic eyes with elevated intraocular pressure (IOP). DESIGN, SETTING, AND PARTICIPANTS Comparative case series o...

AIM To investigate peripheral blood lymphocyte phenotype in patients with intermediate uveitis using CD69, chemokine receptor, and cytokine expression. METHODS Peripheral blood lymphocytes of 18 patients with idiopathic intermediate uveitis and 6 patients with presumed sarcoid intermediate uveitis were evaluated for CD4(+) T cell expression of CD69, CCR4, CCR5, CXCR3 and the intracellular cyt...

Background: Inflammation of the retina, choroid, and nearby tissues such vitreous, optic nerve head, retinal arteries may all occur in posterior uveitis. Aim objectives: This study's primary objective was to use OCT with improved depth focus find changes subfoveal choroidal thickness Subjects methods: Thirty patients uveitis who were visiting ophthalmology departments Al-Azhar University Hospit...

AIM To test the hypothesis that T-bet expression is altered in patients with Vogt-Koyanagi-Harada (VKH) disease. METHODS Peripheral blood was withdrawn from 16 VKH patients before and after immunosuppressive treatment and from 16 healthy individuals. IFN-gamma, IL-2, and IL-4 in the serum and the supernatants of peripheral blood mononuclear cells (PBMC) cultured with or without phytohaemagglu...

PURPOSE Evaluation of peripheral retinal vascular changes in anterior uveitis using ultra-wide-field fluorescein angiography. DESIGN A prospective, observational study of a case series of patients diagnosed with anterior uveitis. METHODS SETTING Clinical observation at an academic medical center. Patient or Study Population: A total of 65 eyes of 33 patients corresponded with the researc...

Uveitis is a leading cause of ocular morbidity, most cases being idiopathic. The advent of steroid therapy has brought about drastic reduction in the incidence of ocular complications of uveitis. However, an array of sideeffects comes along with the benefits of steroids. As noted in our study population, adverse effects of steroids range from increased intraocular pressure and cataract to syste...