background hepatitis b virus (hbv) covalently closed circular dna (cccdna) served as a vital role in the life cycle of the virus and persistent infection. however, specific and quantitative methods for cccdna detection have not been available. objectives our aim was to develop and primarily evaluate a quantitative method for hbv cccdna based on magnetic capture hybridization and quantitative pc...

UNLABELLED : Commonly used multiplicity adjustments fail to control the error rate for reported findings in many expression quantitative trait loci (eQTL) studies. TreeQTL implements a hierarchical multiple testing procedure which allows control of appropriate error rates defined relative to a grouping of the eQTL hypotheses. AVAILABILITY AND IMPLEMENTATION The R package TreeQTL is available ...

The assessment of somatosensory function is a cornerstone of research and clinical practice in neurology. Recent initiatives have developed novel protocols for quantitative sensory testing (QST). Application of these methods led to intriguing findings, such as the presence lower pain-thresholds in healthy children compared to healthy adolescents. In this article, we (re-) introduce the basic co...

rust caused by phakopsora pachyrhizi syd. is a major constraint to soybean product in asia. early detection and possibilities of controlling plant diseases by the integration of several image processing methods has been the subject of extensive research. the main contribution of this paper is to present different methodologies for quantitatively detecting soybean rust at each stage of disease d...