pregabalin (prg) is a new antiepileptic drug and aceclofenac (ace) is a potent non-steroidal anti-inflammatory drug. these drugs in combination are used for treatment of partial seizures and neuropathic pains. a simple and precise assay method by rp-hplc was developed and validated for estimation of prg and ace in acenac-n tablet. analyses of commercial tablet, acenac-n were performed using jas...

aflatoxin m1 (afm1), a carcinogenic substance is found in milk and dairy products. the effect of season and type of dairy products on afmi level in northern iran was investigated in this study.three hundred samples (each season 75 samples) including raw and pasteurized milk, yoghurt, cheese, and cream samples were collected from three distinct milk producing farms. the samples were subjected to...

acrylic base resins are widely used in orthopedics and dental surgery. it is generally accepted that due to the incomplete conversion of methyl methacrylate (mma) monomer to the polymer form during polymerization of the resin, some mma monomers remain in the hardened material. mma monomer has been reported to cause abnormalities or lesions in several organs of animals. study of the literatures ...

Two simple, specific, accurate, precise, sensitive and cost effectivespectrophotometric methods have been developed and validated for quantification oflinagliptin in pure form and pharmaceutical formulations. Method A is established onthe computation of absorbance of purple coloured chromogen complex at 463 nmwhich is formed by the condensation reaction of the primary amine group oflinagliptin ...

The color developing reaction between ambrisentan and 2,3-dichloro-5,6-dicyano-1,4- benzoquinone (DDQ) or 2,5-dichloro-3,6-dihydroxy-1,4-benzoquinone (CLA) was successfully employed in the development of two simple and sensitive spectrophotometric methods (M1 and M2) for the determination of ambrisentan in its pharmaceutical dosage forms.The methods are based on the charge transfer reaction of ...

Background and objectives:Drimia maritima (L.) Stearn also known as squill is a medicinally important plant that has been used for various ailments such as dropsy, respiratory disorders, jaundice and epilepsy from ancient times. Proscillaridin A is identified as one of the most effective compounds in the plant with remarkable pharmacological features including efficacy...

In  the  current  study,  a  new  technique  was  developed  for  quantification  and  qualification  of pseudoephedrine hydrochloride (PSE) in a real sample, which was based on electrochemical sensors and  molecular  imprinted  polymer  (MIP).  The  carbon  paste  electrode  (CPE)  was  modified  and optimized by a different ratio of MIP. MIP/CPE was used as the extraction and working electrod...