نتایج جستجو برای: q15

تعداد نتایج: 199  

2006
Heesook Choi Sencun Zhu Thomas F. La Porta

[S1,Q15=MAC15(S1), P13=MAC13(S1,Q15)] [S2,Q25=MAC25(S2),P23=MAC23(S2,Q25)] [S4,Q46=MAC46(S4),P45=MAC45(S4,Q46)] Q36=MAC36(S1|S2|S3) P35=MAC35(S3, S1|S2, Q15, Q25, Q36) [S3, (S1|S2), Q15, Q25, Q36, P35] Q5B= MAC5B(S1|S2|S3|S4|S5) P56=MAC56(S5, (S1|S2|S3|S4),Q36,Q46,Q5B) [S5, (S1|S2|S3|S4),Q36, Q46, Q5B, P56] P6B=MAC6B(S6, ((S1|S2|S3|S4 |S5)| S7|S8),Q5B,Q7B,Q8B) [S6, ((S1|S2|S3|S4 |S5)| S7|S8),Q5...

Journal: :Applied and environmental microbiology 1998
L G Whyte J Hawari E Zhou L Bourbonnière W E Inniss C W Greer

The psychorotrophic Rhodococcus sp. strain Q15 was examined for its ability to degrade individual n-alkanes and diesel fuel at low temperatures, and its alkane catabolic pathway was investigated by biochemical and genetic techniques. At 0 and 5 degrees C, Q15 mineralized the short-chain alkanes dodecane and hexadecane to a greater extent than that observed for the long-chain alkanes octacosane ...

2012
Hirokazu Shiheido Yuhei Naito Hironobu Kimura Hiroaki Genma Hideaki Takashima Mayuko Tokunaga Takao Ono Tatsuya Hirano Wenlin Du Taketo Yamada Nobuhide Doi Shiro Iijima Yutaka Hattori Hiroshi Yanagawa

We screened 46 novel anilinoquinazoline derivatives for activity to inhibit proliferation of a panel of human cancer cell lines. Among them, Q15 showed potent in vitro growth-inhibitory activity towards cancer cell lines derived from colorectal cancer, lung cancer and multiple myeloma. It also showed antitumor activity towards multiple myeloma KMS34 tumor xenografts in lcr/scid mice in vivo. Un...

2013
Mayuko Tokunaga Hirokazu Shiheido Noriko Tabata Yuko Sakuma-Yonemura Hideaki Takashima Kenichi Horisawa Nobuhide Doi Hiroshi Yanagawa

We recently identified a novel anilinoquinazoline derivative, Q15, as a potent apoptosis inducer in a panel of human cancer cell lines and determined that Q15 targets hCAP-G2, a subunit of condensin II complex, leading to abnormal cell division. However, whether the defect in normal cell division directly results in cell death remains unclear. Here, we used an mRNA display method on a microflui...

Journal: :Applied and environmental microbiology 1999
L G Whyte S J Slagman F Pietrantonio L Bourbonnière S F Koval J R Lawrence W E Inniss C W Greer

We examined physiological adaptations which allow the psychrotroph Rhodococcus sp. strain Q15 to assimilate alkanes at a low temperature (alkanes are contaminants which are generally insoluble and/or solid at low temperatures). During growth at 5 degrees C on hexadecane or diesel fuel, strain Q15 produced a cell surface-associated biosurfactant(s) and, compared to glucose-acetate-grown cells, e...

Journal: :Atlas of Genetics and Cytogenetics in Oncology and Haematology 2013

Journal: :Atlas of Genetics and Cytogenetics in Oncology and Haematology 2020

Journal: :Atlas of Genetics and Cytogenetics in Oncology and Haematology 2011

Journal: :Atlas of Genetics and Cytogenetics in Oncology and Haematology 2011

Journal: :Cancer research 1993
K Mrózek C P Karakousis C D Bloomfield

Cytogenetic study of short-term cultures from 10 adipose tissue tumors (eight lipomas, one myxoid liposarcoma, and one mixed liposarcoma) have revealed clonal chromosome abnormalities in seven cases. In both malignant tumors, translocation (12;16) was the sole aberration, and in the mixed liposarcoma, the breakpoints could be sublocalized to bands 12q13.3 and 16p11.2, thus confirming findings o...

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