Despite six decades of research, the pathogenesis of pyometra is still not completely understood. Recent investigations question whether the previous concept of considering cystic endometrial hyperplasia (CEH)–pyometra as a complex is correct. The pathogenesis of CEH appears to have a strong hormonal component, whereas the etiology of pyometra might be more influenced by the bacterial component...

Cystic endometrial hyperplasia (CEH), mucometra, and pyometra are common uterine diseases in intact dogs, with pyometra being a life threatening disease. This study aimed to determine the gene expression profile of these lesions and potential biomarkers for closed-cervix pyometra, the most severe condition. Total RNA was extracted from 69 fresh endometrium samples collected from 21 healthy fema...

INTRODUCTION Pyometra is an accumulation of purulent material or pus in the uterine cavity. Spontaneous perforation of uterus by pyometra is rare. This is a clinical presentation and management of a spontaneous perforation of uterine caused by pyometra. CASE PRESENTATION This is a case report on spontaneously perforated associated with pyometra secondary to cervical malignancy. The patient un...

Cystic endometrial hyperplasia-pyometra complex, by definition, is the accumulation of purulent material within the uterine lumen of intact bitches, typically occurring during or immediately following a period of progesterone dominance (1, 2). Pyometra is a common disease of adult intact female dogs (3). The mean age of diagnosis is 6-8 years, with a range of 4 to 18 years (4). Ageand breed-rel...

Introduction effects of progesterone on the uterus. The hormonal therapies that include either progesterone for estrous Canine Pyometra is a common reproductive suppression or estrogen for estrous induction or disorder of intact, diestrual bitch which affects nearly pregnancy termination may explain the development of one fourth of all female dogs before they reach ten pyometra in young bitches...

Reprint requests to: Dr. Jiun-Kai Fan Department of Radiology, Hsinchu Cathay General Hospital. No. 678, Sec. 2, Jung Hua Road, Hsinchu, 300, Taiwan, R.O.C. Pyometra refers to pus accumulation in the uterine cavity, which is usually seen in older women. Because most sufferers present nonspecific symptoms, a correct diagnosis is usually not made until operation for a ruptured pyometra. Pyometra ...

Endometritis-pyometra is the most frequent and complex pathology in domestic bitches. This process involves several immunological changes as well as molecular mechanisms responsible for inflammation in the female uterus. The various clinical stages of pyometra are associated with various symptoms. In this review, several aspects are described, including physiological and pathological mechanisms...

Pyometra is an uncommon condition in general population and caused by impairment of natural drainage of the cervix as a result of benign or malignant diseases. Spontaneous uterine perforation, a very rare complication of pyometra, carries signifi cant morbidity and mortality and should be considered in the differential diagnosis of other peritonitis. Preoperative diagnosis of perforated pyometr...

Fransson, B. 2003. Systemic inflammatory response in canine pyometra; the response to uterine bacterial infection. Doctor’s dissertation. ISSN 1401-6257, ISBN 91-576-6393-9. Research efforts have focused mainly on the hormonal aspects of canine pyometra for more than 6 decades. However, this disease is often manifested as systemic illness in response to the bacterial uterine infection. Studies ...

The objective was to determine whether occurrence of persistent corpora lutea in cows with pyometra could be explained by accumulation of prostaglandins and interferons in the uterus. Pyometra was induced by treatment with hCG, followed by intrauterine infusions of iodine and Actinomyces pyogenes . Five of the seven treated cows developed pyometra as indicated by extended estrous cycles (30-37 ...