نتایج جستجو برای: pvp k 30

تعداد نتایج: 870408  

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه پیام نور - دانشگاه پیام نور استان تهران - دانشکده کشاورزی 1393

چکیده برای هزاران سال، کورکومین در شرق به عنوان یک عامل درمانی برای طیف گسترده ای از بیماری های التهابی، نئوپلاستی و دیگر شرایط استفاده شده است. در سال های اخیر، پتانسیل درمانی بزرگی برای این ترکیب در برابر بیماری های مختلف انسان از جمله سرطان، بیماری های قلبی و عروقی، دیابت، ورم مفاصل، بیماری های عصبی و بیماری hivگزارش شده است. این ترکیب اثرات خود را از طریق کاهش بروز فاکتورهای نسخه برداری ا...

2015
K. P. R. CHOWDARY K. RAVI V. V. L. S. P. SOWJANYA

Irbesartan, a widely prescribed anti hypertensive drug belongs to class II under BCS classification and exhibit low and variable oral bioavailability due to its poor aqueous solubility. It needs enhancement in the dissolution rate in its formulation development. Complexation with β-cyclodextrin (βCD) and use of Crospovidone and PVP K 30 are tried for enhancing the dissolution rate of irbesartan...

2011
H. Xu T. Zhang H. Yang X. Xiao Y. Bian D. Si C. Liu

In order to increase the dissolution rate and bioavailability, solid dispersions of evodiamine in PVP K(30) with different enriched samples of evodiamine to PVP K(30) ratios were prepared by solvent method. Our studies showed that the dissolution rate of evodiamine was significantly higher in the solid dispersion system in comparison with that in enriched samples of evodiamine or physical mixtu...

2010
Subash Pillai

An attempt was made to formulate Buccal patches of Isoxsuprine hydrochloride, a potent and long acting vasodilator and uterine suppressant , by using Hydroxyl propyl methyl cellulose(HPMC), Polyvinyl pyrolidone K-30 (PVP K-30) and Hydroxyl ethyl cellulose (HEC). Twelve batches of buccal patches were prepared by solvent casting technique in which the best formulation was found out. The polymers ...

Journal: :Journal of pharmaceutics 2013
Jyothi Sanaboina K M Maheswari Seetha Sunkara Sravanthi Deekonda Buchi N Nalluri

The present investigation includes the preparation of liquid filling formulations for soft gels using an antihypertensive drug, valsartan (VAL), in order to improve its dissolution properties and thereby its bioavailability. Formulations were prepared using excipients like polyethylene glycol 400 (PEG 400), propylene glycol (PG), polyvinylpyrrolidone (PVP K-30), antioxidants, ethanol, and purif...

Journal: :Acta pharmaceutica 2007
Vishnu M Patel Bhupendra G Prajapati Madhabhai M Patel

Mucoadhesive buccal patches containing propranolol hydrochloride were prepared using the solvent casting method. Chitosan was used as bioadhesive polymer and different ratios of chitosan to PVP K-30 were used. The patches were evaluated for their physical characteristics like mass variation, drug content uniformity, folding endurance, ex vivo mucoadhesion strength, ex vivo mucoadhesion time, su...

Journal: :Drug discoveries & therapeutics 2011
A Ali A Trehan Z Ullah M Aqil Y Sultana

Matrix type transdermal therapeutic systems (TTS) of glibenclamide were formulated using polymers Eudragit RL 100, ethyl cellulose, PVP K-30, and polyvinyl acetate, and citral was used as the penetration enhancer. The polymer films were formulated with Eudragit RL 100 and PVP K-30 in different ratios and subsequently subjected to ex vivo studies (drug permeation through rat skin) followed by in...

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