background atopic dermatitis (ad) is a chronic inflammatory skin disease. phototherapy is considered as an effective treatment modality in severe cases. objectives in this study, we proposed to evaluate the efficacy of bath puva (psoralen plus ultraviolet a) in the treatment of severe and atopic dermatitis. patients and methods twenty-eight patients with severe atopic dermatitis were included i...

Palmoplantar psoriasis is a chronic disease, which is very resistant to treatment and often leads to severe disabilities. Photochemotherapy employing psoralens combined with UVA irradiation (PUVA) is a well-accepted therapy for palmoplantar psoriasis. Its topical application (bath PUVA; cream PUVA) avoids the typical side effects of orally applied psoralens. We compared the efficacy of cream PU...

OBJECTIVE To compare the efficacy of oral psoralen-UV-A (PUVA) with that of narrowband-UV-B (NB-UVB) phototherapy in patients with nonsegmental vitiligo. DESIGN Double-blind randomized study. SETTING Phototherapy unit in a university hospital. PATIENTS Fifty-six patients with nonsegmental vitiligo. Interventions Twice-weekly therapy with PUVA or NB-UVB. MAIN OUTCOME MEASURES The change ...

Psoralen plus ultraviolet A (PUVA) is widely used as first-line therapy for treatment of mycosis fungoides. Narrowband ultraviolet B (NB-UVB) has also been shown to be effective for treatment of early mycosis fungoides. The aim of this retrospective study was to analyse the response to treatment and relapse-free interval for PUVA and NB-UVB therapies in mycosis fungoides. Forty patients were tr...

Three age- and sex-matched groups of 30 patients with chronic plaque psoriasis were treated by photochemotherapy (PUVA). Groups I and II received routine maintenance PUVA therapy at different intervals and Group III had no maintenance treatment. The remission time after the clearance treatment with PUVA is compared with the total cumulative dose of long wave ultraviolet light (UVA). A lower mea...

PUVA therapy is widely used for early stage mycosis fungoides. While the efficacy of PUVA with oral 8-methoxypsoralen (8-MOP) is well documented, the use of its topical variation, bath-water PUVA therapy with 8-MOP has not been studied. The purpose of this study was to assess the effect of 8-MOP bath-water PUVA therapy in adult patients with early stage mycosis fungoides. We retrospectively eva...

we present a 21-years old woman with alopecia universalis, generalized vitiligo, and graves' disease. she had had thyroidectomy in early childhood and was receiving replacement therapy with levothyroxine. the patient was treated with systemic puva and glucocorticoid in combination with topical treatment for alopecia. after 6 months of treatment, alopecia was reversed but vitiligo was unchanged.