BACKGROUND Herbal drugs are considered alternative agents and have been used for several years around the world. Recurrent aphthous stomatitis (RAS) is one of the most common problems recognized by dentists and skin specialists. This problem is characterized by recurring, painful, small oral mucosal ulcers with a round or oval aspect that mostly appear in keratinized mucosa, cheeks, and on the ...

The Punica granatum L. var. granatum (pomegranate) has been demonstrated to exert antitumor effects on various types of cancer cells. The present study aimed to evaluate the medicinal herbs Punica granatum L. var. spinosa (apple punice) that are native to Iran. This study was determined to test the possible cytotoxic activity and induction of apoptosis on human prostate cell lines. The effect o...

PURPOSE Punica granatum L. var. granatum (Pomegranate), an herbaceous plant found in Iran, The aim of this study was to investigate the cytotoxic effects, induction of apoptosis, and the mechanism of cell death of ethanol extract from Punica granatum L. var. spinosa on the mouse fibrosarcoma cell line, WEHI-164. METHODS Various parts of the herbs were extracted from fruit using ethanol as the...

    Background and objectives: Halitosis as a common dentistry ailment which has a prevalence of around 50% of the adult population. There are many dental formulations in traditional Persian pharmacy called “Gharagher”, “Mazmazeh”, “Sonoun”, etc for treatment of halitosis. In the present study, we have tried to describe the step by step moder...

In our previous studies, we showed the inhibitory effects of Punica granatum L. flower and Rhus coriaria L. fruit water extracts on dental plaque accumulation by several bacteria, especially Streptococcus mutans (S. mutans), on orthodontic wire by in-vitro assays. In this study, the anti-cariogenic properties of the extracts were evaluated by assessing their effects on expression of glycosyltra...

Pomegranate (Punica granatum) is an ancient fruit used in various systems of medicine for a variety of ailments. The study has been designed to investigate the role of ethanolic extract of rinds of Punica granatum as antimicrobial on 6 types of bacteria includes; Pseudomonas aeruginosa, Salmonella typhi, Staph aureus, E.coli, Streptococcus spp. and Klebsiella pneumonia and antifungal activity o...