pulmonarytoxicity

Gene Expression and Pulmonary Toxicity of Chitosan-graft-Polyethylenimine as Aerosol Gene Carrier

Journal: The Iranian Journal of Pharmaceutical Research 2013

Arash Minai-Tehrani, Chang Gyu Woo, Chong-Su Cho, Hu-Lin Jiang, Jung-Taek Kwon, Mansoo Choi, Myung-Haing Cho, Yeon-Soo Kim,

Chitosan-graft-polyethylenimine (CHI-g-PEI) copolymer has been used for theimprovement of low transfection efficiency of chitosan. The present study aims to test thepulmonary toxicity and efficiency of CHI-g-PEI as an aerosol gene carrier. Mice were exposedto aerosol containing green-fluorescent protein (GFP)-polyethylenimine (PEI) or GFP-CHIg-PEI complexes for 30 min during the development of ...

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Gene Expression and Pulmonary Toxicity of Chitosan-graft-Polyethylenimine as Aerosol Gene Carrier

Journal: Iranian Journal of Pharmaceutical Research 2013

Arash Minai-Tehrani, Chang Gyu Woo, Chong-Su Cho, Hu-Lin Jiang, Jung-Taek Kwon, Mansoo Choi, Myung-Haing Cho, Yeon-Soo Kim,

Chitosan-graft-polyethylenimine (CHI-g-PEI) copolymer has been used for theimprovement of low transfection efficiency of chitosan. The present study aims to test thepulmonary toxicity and efficiency of CHI-g-PEI as an aerosol gene carrier. Mice were exposedto aerosol containing green-fluorescent protein (GFP)-polyethylenimine (PEI) or GFP-CHIg-PEI complexes for 30 min during the development of ...

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gene expression and pulmonary toxicity of chitosan-graft-polyethylenimine as aerosol gene carrier

Journal: :iranian journal of pharmaceutical research 0

jung-taek kwon laboratory of toxicology, college of veterinary medicine, seoul 151-742, korea. hu-lin jiang 1- laboratory of toxicology, college of veterinary medicine, seoul 151-742, korea. 2- school of pharmacy, china pharmaceutical university, nanjing 210009, china. arash minai-tehrani laboratory of toxicology, college of veterinary medicine, seoul 151-742, korea. chang gyu woo nanotechnology and thermal processing laboratory, school of mechanical and aerospace engineering, seoul 151-742, korea. mansoo choi nanotechnology and thermal processing laboratory, school of mechanical and aerospace engineering, seoul 151-742, korea. chong-su cho research institute for agriculture and life sciences, seoul national university, seoul 151-742, korea.

chitosan-graft-polyethylenimine (chi-g-pei) copolymer has been used for theimprovement of low transfection efficiency of chitosan. the present study aims to test thepulmonary toxicity and efficiency of chi-g-pei as an aerosol gene carrier. mice were exposedto aerosol containing green-fluorescent protein (gfp)-polyethylenimine (pei) or gfp-chig-pei complexes for 30 min during the development of ...

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