patients with pulmonary cavities are usually exposed to other pulmonary infections, especially of fungus origin, such as asnprgillosis and coccidiomycosis. they are manifested by the formation of fungus ball in these cavities, which is completely resistant to anti-fungal therapy. in these circumstance the best method of treatment is removing of the ball by surgery, in this paper a case of pulmo...

background: intensified strategy includes special attention to the symptoms such as cough (more than two weeks), fever (more than three weeks), night sweats (more than three weeks), and weight loss (more than 3 kg per month). if any of the above symptoms was positive, in suspected individuals for tb, more assessment should be done. the aim of this study was to compare between intensified and ro...

conclusions the development of delivery systems into bacteria with an efficacy compatible to that in human use could be a key for the potential utility of sirna for the prophylaxis and treatment of p. aeruginosa-induced hematogenous pulmonary infections in humans. results in quantitative rt–pcr,it was shown that the sirna significantly inhibited the expression of the flagella mrna. filc gene kn...

background in spite of recent advents, and novel improvements in the diagnosis and treatment of pulmonary tuberculosis (tb), definitive diagnosis of pulmonary tb in children is problematic. therefore, measurement of the serum level of adenosine deaminase (ada) was later introduced as a helpful marker for the diagnosis of tb. objectives the purpose of this study was to determine the usefulness o...

The potentially pathogenic Non-Tuberculosis Mycobacteria (NTM) are emerging nowadays which result in pulmonary and non-pulmonary infections in human. This group of bacteria consists of at least 200 different species. While the pulmonary disease is the most common form of NTM infections, NTM can cause diffused infections as well as extrapulmonary infections in every organ, such as bone marrow, s...

chronic granulomatous disease (cgd) is a rare disorder of phagocytes, predisposes patients to bacterial and fungal infections. the main purpose of this study was to determine the clinical, radiological, pathologicial features, outcome and response to treatment of children with cgd. thirteen patients with cgd, who had been referred to national research institute of tuberculosis and lung disease ...

Background: With increasing immunocompromised patients, fungal infections especially lung infection, have also increased. In this study, fungal contamination of the respiratory system in immunocompromised patients was evaluated. Methods: This descriptive cross-sectional study was conducted in immunocompromised patients suspicious of pulmonary infections referring to specialized lung clinic of ...

Infections in the respiratory tract are very common but majority involve the upper respiratory system. Pneumonia is usually caused by inhalation of infecting organisms or the same may reach the lung via bloodstream. Pulmonary pathogens can cause tissue damage by a direct invasive cytolytic process or by releasing toxins (endotoxins and/or exotoxins). Acute inflammation may lead to complete reso...