background nasal septal deviation (nsd) can cause upper airway obstruction, which results in hypoxia and therefore, pulmonary vasoconstriction, ventricular hypertrophy and right-sided heart failure. objectives the aim of this study is to determine the mean pulmonary arterial pressure (mpap) of the patients with nsd and the effect of septoplasty on pulmonary arterial pressure. patients and metho...

conclusions our case highlights the fact that the tip of the pulmonary artery catheter can easily advance into a peripheral branch of the pulmonary artery and cause pulmonary venous blood to be sampled instead of pulmonary arterial blood. a variety of monitoring techniques are needed to confirm accurate catheter placement. background pressure and waveform at the catheter tip are continuously mo...

background the nasal septal deviation (nsd) is one of the major causes of nasal obstruction. this condition increases upper airway resistance. in this study we evaluated the mean pulmonary artery pressure (mpap) in patients with markedly deviated septum. methods sixty two patients with nsd (age range: 26-45 years, 34 men and 28 women) were included in the study. mean pulmonary artery pressure w...

Background: Alveolar hypoxia induces monophasic pulmonary vasoconstriction in vivo, biphasic vasoconstriction in the isolated pulmonary artery, and controversial responses in the isolated perfused lung. Pulmonary vascular responses to sustained alveolar hypoxia have not been addressed in the isolated perfused rat lung. In this study, we investigated the effect of sustained hypoxic ventilation o...

background: alveolar hypoxia induces monophasic pulmonary vasoconstriction in vivo, biphasic vasoconstriction in the isolated pulmonary artery, and controversial responses in the isolated perfused lung. pulmonary vascular responses to sustained alveolar hypoxia have not been addressed in the isolated perfused rat lung. in this study, we investigated the effect of sustained hypoxic ventilation o...

conclusions based on the results of this study, we suggest the use of a novel “time from the beginning of isovolumetric contraction to the peak of the s wave” (ttp) parameter in the tdi of the base of the rv free wall to predict ph with acceptable accuracy in comparison with rhc. results in our study, the ttp showed a significant inverse relationship with the pap. based on our results, a ttp of...

Objective(s): The present study was aimed to investigate the influence of thoracic epidural blockade on hypoxia-induced pulmonary hypertension in rats. Materials and Methods: Forty eight Wistar rats were randomly divided into 4 equal groups, named normoxia hypoxia hypoxia/ ropivacaine and hypoxia/saline. Animals were placed in a hypoxia chamber and instrumented with epidural catheters at the t...

Background: Vitamin D (Vit D) is linked to various conditions including musculoskeletal, metabolic and   cardiopulmonary diseases. However, it is not clear whether correction of vit D deficiency exerts any beneficial effect in patients with pulmonary hypertension. Methods: This study was a prospective uncontrolled longitudinal study. Patients with pulmonary hypertension and vit D d...