Psychogenic purpura (Gardner-Diamond syndrome) is the occurrence and spontaneous recurrence of painful ecchymosis following emotional stress and minor trauma. Although the exact mechanism of this syndrome remains unknown, apart from skin lesions, different types of hemorrhaging have been reported, such as epistaxis, gastrointestinal bleeding, and bleeding from the ear canals and eyes. We report...

autoerythrocyte sensitization syndrome cabs) is a rare purpuric disorder of women characterized by inflammatory and painful ecchymotic lesions unrelated to blood clotting or vascular abnormalities. gastrointestinal bleeding, hematuria, headache or syncopal attacks may also be observed. our patient is a 33-year-old woman presenting with recurrent severe painful ecchymotic lesions on both lower e...

The above quotation is taken from the original clinical report in which Gardner and Diamond (1955) described the syndrome of autoerythrocyte sensitization as an unusual purpuric syndrome in which crops of apparently spontaneous painful inflammatory ecchymoses occurred in four women who had sustained physical injury shortly before the onset of symptoms. They postulated that, as a result, their p...

Psychogenic purpura (PP) or Gardner-Diamond syndrome is a very rare condition characterized by spontaneous, recurrent, and painful edematous skin lesions progressing to ecchymoses [1]. Bleeding from the nose, gastrointestinal organs, kidneys, and uterus has also been reported [2]. PP is commonly regarded as an autoimmune vasculopathy with sensitization to phosphatidylserine, a component of eryt...