conclusions prp dressing could significantly decrease the depth and surface area of dfus in a three-week period. background some of the studies confirmed the effectiveness of platelet rich plasma (prp) in the treatment of diabetic foot ulcers (dfu). however, these studies had small sample size and used different methods such as prp gel or prp injections. the results are also contraversial. obje...

Ulcers, especially in the lower limb are a frequent problem encountered in our hospitals and are often difficult to heal because they lack the necessary growth factors to maintain the healing process, and are frequently complicated by superinfection. Conventional therapies such as dressings and surgical debridement cannot provide satisfactory healing since these treatments are not able to provi...

objective: to assess the effects of platelet rich plasma (prp) with chitosan biodegradable film on full thickness wound healing in rat. methods: this was an experimental study being performed in 2015 during a 4-month period. twenty-four male white wistar rats were divided into four groups of 12 rats each, randomly: control group (sham) with creation of wounds and no treatment, prp group with cr...

INTRODUCTION Chronic skin ulcers, such as diabetic ulcers, venous leg ulcers and pressure ulcers, are intractable and increasing in prevalence, representing a costly problem in healthcare. We developed a combination therapy with a gelatin sheet, capable of providing sustained release of platelet-rich plasma (PRP). The objective of this study is to investigate the safety and efficacy of autologo...

Traditional therapeutic methods for skin wounds have many disadvantages, and new wound dressings that can facilitate the healing process are thus urgently needed. Platelet-rich plasma (PRP) contains multiple growth factors (GFs) and shows a significant capacity to heal soft tissue wounds. However, these GFs have a short half-life and deactivate rapidly; we therefore need a sustained delivery sy...

In the past decade, autologous platelet-rich plasma (PRP) therapy has seen increasingly widespread integration into medical specialties. PRP application is known to accelerate wound epithelialization rates, and may also reduce postoperative wound site pain. Recently, we observed an increase in patient satisfaction following PRP gel (Angel, Cytomedix, Rockville, MD) application to split-thicknes...

BACKGROUND Platelet-rich plasma (PRP) contains high concentrations of growth factors involved in wound healing. Hydrogel is a 3-dimensional, hydrophilic, high-molecular, reticular substance generally used as a dressing formulation to accelerate wound healing, and also used as a bio-applicable scaffold or vehicle. This study aimed to investigate the effects of PRP and hydrogel on wound healing, ...

this case report describes a 59-year-old woman with a giant basal cell carcinoma on the face neglected for 11 years. surgical resection of the lesion resulted in a 13 × 11 cm defect. issues regarding the adequately safe surgical margins and the management of the resultant defect through modern wound dressing technologies are discussed. keywords : giant basal cell carcinoma, modern dressing, gel...