egfr is a key molecule in cancer cells. egfr signaling was shown to promote tumor cell proliferation and survival, invasion and angiogenesis and mediate resistance to treatment, including ionizing radiation in preclinical models. we extracted proteins from astrocytoma (iii and iv) oligodendroglioma(iv) tumors and normal brain tissues and then evaluated the protein purity by bradford test and sp...

background: dihydropyrimidinase related proteins (drps) have known homologous to the collapsing response mediator proteins (crmps). the drp gene family has comprised four members, drp 1, 2, 3, and 4, all out of which have considered to be involved in axonal outgrowth and path-finding. methods: the protein has extracted from tumor, normal brain tissues, and then the protein purity has evaluated ...

background : glioblastoma multiforme (gbm) or grade iv astrocytoma is the most common and lethal adult malignant brain tumor. several of the molecular alterations detected in gliomas may have diagnostic and/or prognostic implications, proteomics has been widely applied in various areas of science, ranging from the deciphering of molecular pathogen nests of discuses. method: we extracted protein...

      EGFR is a key molecule in cancer cells. EGFR signaling was shown to promote tumor cell proliferation and survival, invasion and angiogenesis and mediate resistance to treatment, including ionizing radiation in preclinical models. We extracted proteins from astrocytoma (III and IV) oligodendroglioma(IV) tumors and normal brain tissues and then evaluated the protein purity by Bradford test ...

proteins are fundamental components of cells which mediate many essential biological processes. proteomics is a rapidly growing field for the study of proteome, the protein complement expressed by the genome of an organism or cell type. the large-scale analysis of proteins leads to a more comprehensive view of molecular and cellular pathways that improves the overall understanding of the comple...

BACKGROUND Glioblastoma Multiforme (GBM) or grade IV astrocytoma is the most common and lethal adult malignant brain tumor. Several of the molecular alterations detected in gliomas may have diagnostic and/or prognostic implications. Proteomics has been widely applied in various areas of science, ranging from the deciphering of molecular pathogen nests of discuses. METHODS In this study protei...

stress is a threatening factor that all living organisms encounter throughout life. depending on the type of stress, there are several mechanisms for keeping body homeostasis to minimize stress effects. brain is an organ which shows high sensitivity to stress conditions. although many studies have shown induced-stress effects on rat embryos, little is known about the mechanisms involved in copi...

Background: The numerous methods and techniques employed in proteomics investigations generate vast quantities of heterogeneous data, both results and provenance. A standard representation of proteomics data and techniques is urgently required in order to document a proteomics investigation. A standard representation will facilitate data exchange, verification and further analysis, and pr...

Presentations at the 2008 meeting of the American Electrophoresis Society dealt with many aspects of this key separation technology. In total, there were 65 technical talks and 13 posters in a 4-day meeting. The proteomics technical talks described applications of 1D and 2D gel electrophoresis, capillary electrophoresis and microscale platforms. Some new platforms may find use in future proteom...