the hydrophobic proteins of plant plasma membrane still remain largely unknown.  for example in the arabidopsis genome, receptor-like kinases (rlks) are plasma membrane proteins, functioning as the primary receptors in the signaling of stress conditions, hormones and the presence of pathogens form a diverse family of over 610 genes. a limited number of these proteins have appeard in protein pro...

we have investigated the effect of theophylline on the kinetics of the catalytic subunit of protein kinase and related factors in lung tissue. the results show that the point of highest concentration of the c subunit of protein kinase which is active in casein phosphorylation is at 3h of incubation time, but in the presence of 100 ilg/ inl and 10µg/ml theophylline, this is shifted to i.s and 2....

how to cite this article: fallah e, arman a, najafi m, shayegh b. effect of tamoxifen and lithium on treatment of acute mania symptoms in children and adolescents. iran j child neurol. spring 2016; 10(2):16-25. abstract objective many studies have supported the role of protein kinase c (pkc) inhibitors in the physiopathology and treatment of bipolar disorder in adults. tamoxifen is one of the d...

conclusions these results showed enhanced muscle atrophy processes following peripheral nerve damage and might provide a useful approach to study underlying muscle mechanisms associated with clinical neuropathic pain syndromes. results compared to control animals, l5 ligated animals developed mechanical and heat hypersensitivity during total period of study. soleus muscle weight as well as cdk5...

antiproliferative protein (app) isolated from conditioned media of two androgen-independent prostatic carcinoma cell lines, pc3 and du-145 was shown to inhibit selectively cell proliferation of androgen-dependent prostate cancer cell line lncap in a dose dependent manner. this protein was further purified with hplc using hydrophobic interaction column (phenyl 5pw) and was used to study the modu...

Antiproliferative protein (APP) isolated from conditioned media of two androgen-independent prostatic carcinoma cell lines, PC3 and Du-145 was shown to inhibit selectively cell proliferation of androgen-dependent prostate cancer cell line LNCaP in a dose dependent manner. This protein was further purified with HPLC using hydrophobic interaction column (phenyl 5PW) and was used to study the modu...

Glutamate, as an essential neurotransmitter, has been thought to have different roles in the central nervous system (CNS), including nerve regeneration, synaptogenesis, and neurogenesis. Excessive glutamate causes an up-regulation of the multiple signaling pathways, including phosphoinositide-3 kinase/protein kinase B (PI3K/Akt), Akt/mammalian target of rapamycin (mTOR) protein, mitogen-activat...

patients with diabetes mellitus (dm), experience significant morbidity and mortality from microvascular retinopathy, nephropathy and neuropathy. hyperglycemia can induce diabetic complications through multiple pathways. activation of protein kinase c (pkc) by hyperglycemia is one of the pathways which causes diabetic complications. effect of nifedipine (a calcium channel blocker), and polymyxin...

evidence acquisition the fifty two significant articles discussing the stem cell in chronic myeloid leukemia from 1996 to 2012 were selected according to the authors’ experience. results studies have shown that primitive cml cells are less responsive to tyrosine kinase inhibitors (tkis) and are a reservoir for the relapse of multi drug resistant (mdr). conclusions following that, minimal residu...