background prostate is an important male reproductive system gland and its disorders can affect men's quality of life and health. prostatitis, benign prostatic hyperplasia (bph), and prostate adenocarcinoma are major disorders that can be found in all men in different ages. objectives the aim of this study was to investigate the association of diet with serum prostate specific antigen (psa) lev...

the tp53 gene is one of the most frequently mutated genes amongst human malignancies, particularly tp53 codon 72 polymorphism. furthermore, an association between the tp53 codon 72 variants and prostate cancer has been reported in several studies. although some studies have indicated an association between the tp53 arg/arg variant and an increased risk for prostate cancer, other studies have sh...

background: prostate specific antigen (psa) is a protein currently used in vconjunction with the digital rectal examination to detect and guide management of prostate cancer. there are several causes of increase in serum psa including urological manipulations, medications, prostatic diseases, prostate cancer, prostate inflammation or infection, etc. some studies had reported cystoscopy to cause...

Objective(s): Prostate cancer is the world’s leading cause of cancer and the second cause of cancer-related death in men after lung cancer. Differentiation of prostate adenocarcinoma from benign prostate lesions and hyperplasia sometimes cannot be done on the basis of morphologic findings. Considering the fact that in the prostate adenocarcinoma there is no basal cell layer, basal cell markers ...

benign prostatic hyperplasia (bph) is a common disease in human that gradual overgrowth of the prostate gland leads to impinge on the urethra with impairment in urinary function. numerous plants improve uncontrolled growth of the prostate gland and improve urinary tract symptoms associated with bph. in this study, 25 healthy adult male wistar rats were divided randomly in five groups: g1 (contr...

objective(s): prostate cancer is the world’s leading cause of cancer and the second cause of cancer-related death in men after lung cancer. differentiation of prostate adenocarcinoma from benign prostate lesions and hyperplasia sometimes cannot be done on the basis of morphologic findings. considering the fact that in the prostate adenocarcinoma there is no basal cell layer, basal cell markers ...

background : insulin-like growth factor-1 can act in both an autocrine and paracrine manner to promote normal growth and malignant cellular proliferation. the importance of this factor as a major regulatory peptide has been established for cells, in vitro and in vivo. however, the role of serum insulin-like growth factor-1 levels in the etiology of benign prostatic hyperplasia and prostate canc...

results in a total of 40 sporadic prostate cancer and 80 benign prostatic hyperplasia cases, no xmrv was detected by real-time pcr and nested-pcr. rnase l r462q polymorphism analysis reveals that although there was an increase in the risk of prostate cancer correlated with the q/q allele of rnase l at position 462, the frequencies of the rnase l r462q alleles were not statistically significant ...