Aim: To compare effectiveness and safety of double balloon catheter prostaglandins for induction labor. Methods: an observational ambidirectional cohort study was conducted at a tertiary care university hospital. A total 666 women with Bishop score ≤6 requiring labor were included. 418 patients compared retrospective 248 induced prostaglandins, either misoprostol or dinoprostone. Perinatal outc...

Dysmenorrhea is called "primary" when there is no specific abnormality and "secondary" when the pain is caused by an underlying gynecological problem. It is believed that primary dysmenorrhea occurs when hormone-like substances called "prostaglandins" produced by uterine tissue trigger strong muscle contractions in the uterus during menstruation. However, the level of prostaglandins does not se...

sulfur mustard, a bifunctional alkylating agent, causes severe eye injury. the injury is a result of late inflammation, which is mediated by prostaglandins. theoretically, inhibition of prostaglandins by reagents such as indomethacine could result in alleviation of clinical adverse effects. in this study, the protective effect of topically applied indomethacine against sulfur mustard toxicity w...

Knowledge of the structure and synthesis of antibodies (immunoglobulins) has developed to a remarkable degree in the last decade. Distinct classes of immunoglobulin (yG, yM, -yA, yD, yE, and their subgroups) have been identified and shown to consist of fixed numbers of light and heavy polypeptide chains organized in pairs. Each polypeptide has a segment of variable amino acid sequence; the spec...

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prostaglandin £j (pge-^) and indomethacin, a nonstroidal antiinflammatory drug, were separately administered during ortliodontic tooth movement in rats. at the beginning, an orthodontic appliance was placed and activated in male albinos rats. in tlie first examination, the experimental group received submucosal injections of pge-y (10 mg/kg/day) near the first maxillary riglit molars, and alcoh...

We report a unified chemoenzymatic asymmetric synthesis of five prostaglandins, featuring two enzymatic redox transformations and copper(ii)-catalyzed regioselective p-phenylbenzoylation.

the effect of intracerebroventricular injections of prostaglandins e2 and f2a was studied on the rectal temperature of sheep. pge2 but not pgf2a at the same dose of 50mg elevated the 1h post-injection of rectal temperature. pge2 but not pgf2a at the same dose of 100mg increased 3.5 and 2h post-injection of rectal temperature, respectively. elavation of rectal temperature following pge2 and pgf2...