نتایج جستجو برای: proscillaridin a

تعداد نتایج: 13431805  

2010
Katarzyna Winnicka Krzysztof Bielawski Anna Bielawska

The objective of this study was to determine the cytotoxicity, antiproliferative activity, and apoptosis induction activity of two modified glycosides – digoxin and proscillaridin A – conjugated to a generation 3 polyamidoamine dendrimer (G3 PAMAM-NH ) in human breast cancer cells. The results suggest that conjugation with the G3 PAMAM-NH dendrimer enhances the cytotoxicity of modified digoxin ...

2014
Emilie Denicolaï Nathalie Baeza-Kallee Aurélie Tchoghandjian Manon Carré Carole Colin Carine Jiguet Jiglaire Sandy Mercurio Christophe Beclin Dominique Figarella-Branger

Glioblastoma is the most frequent primary brain tumor in adults. Because of molecular and cellular heterogeneity, high proliferation rate and significant invasive ability, prognosis of patients is poor. Recent therapeutic advances increased median overall survival but tumor recurrence remains inevitable. In this context, we used a high throughput screening approach to bring out novel compounds ...

Journal: :Folia Pharmacologica Japonica 1973

Gh. Amin M. Bozorgi M. Shekarchi S. Kasebzade

Background and objectives:Drimia maritima (L.) Stearn also known as squill is a medicinally important plant that has been used for various ailments such as dropsy, respiratory disorders, jaundice and epilepsy from ancient times. Proscillaridin A is identified as one of the most effective compounds in the plant with remarkable pharmacological features including efficacy...

Journal: :research journal of pharmacognosy 0
m. bozorgi department of traditional pharmacy, faculty of traditional medicine, tehran university of medical sciences, tehran, iran. gh. amin department of pharmacognosy, faculty of pharmacy, tehran university of medical sciences, tehran, iran. s. kasebzade pharmaceutical sciences branch, islamic azad university, tehran, iran. m. shekarchi food and drug laboratory research center, food and drug control laboratories, moh and me, tehran, iran.

background and objectives:drimia maritima (l.) stearn also known as squill is a medicinally important plant that has been used for various ailments such as dropsy, respiratory disorders, jaundice and epilepsy from ancient times. proscillaridin a is identified as one of the most effective compounds in the plant with remarkable pharmacological features including efficacy against congestive heart ...

Journal: :research journal of pharmacognosy 0
m. bozorgi department of traditional pharmacy, school of traditional medicine, tehran university of medical sciences, tehran, iran. g.r. amin department of pharmacognosy, school of pharmacy, tehran university of medical sciences, tehran, iran. s.n. ostad department of toxicology and pharmacology, pharmaceutical sciences research center, school of pharmacy, tehran, iran. n. samadi department of drug and food control, school of pharmacy and phamaceutical quality assurance research center, tehran university of medical sciences, tehran, iran. e. nazem department of traditional medicine, school of traditional medicine, tehran university of medical sciences, tehran, iran. m. shekarchi food and drug laboratory research center and food and drug control laboratories, moh and me, tehran, iran.

background and objectives:  squill [drimia maritima (l.) stearn] is an important medicinal plant that has been used for medicinal purposes such as cardiovascular diseases and asthma since ancient times. bufadienolides are the main compounds of this plant and are responsible for some reported adverse effects. in order to reduce adverse effects, different methods like boiling with vinegar were ap...

E. Nazem G.R. Amin M. Bozorgi M. Shekarchi N. Samadi S.N. Ostad

Background and objectives:  Squill [Drimia maritima (L.) Stearn] is an important medicinal plant that has been used for medicinal purposes such as cardiovascular diseases and asthma since ancient times. Bufadienolides are the main compounds of this plant and are responsible for some reported adverse effects. In order to reduce adverse effects, differen...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد علوم دارویی - پژوهشکده گیاهان دارویی 1393

پیاز عنصل با نام علمی drimia maritia ، یکی از گیاهان دارویی مهم است که در طب سنتی برای درمان بیماری های مختلفی از جمله ورم، اختلالات تنفسی، زردی و صرع کاربرد داشته است. بوفادینولیدها به عنوان ترکیبات اصلی این گیاه شناسایی شده اند. ترکیب بوفادینولیدی این گیاه proscillaridin است که خواص فارماکولوژیک زیادی دارد. از اثرات درمانی پروسیلاریدین می توان به این موارد اشاره کرد: اثربخشی علیه نارسایی احت...

2011
Daigo Yamamoto Satoshi Watanabe Minoru T. Miyahara

Dendrimer-encapsulated Pt nanoparticles can be synthesized by Pt2þ coordination with dendrimers followed by reduction. In the present study, we have systematically investigated the coordination kinetics of PtCl4 2 with fourth-generation hydroxyl-terminated poly(amidoamine) (PAMAM G4-OH) dendrimers using UV vis spectroscopy measurements. Our experimental investigation clarifies that Pt2þ coordin...

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