Background and Objective: Breast cancer is the commonest cancer of Indian women. Estrogen and Progesterone expression is seen in benign breast lesions and in breast carcinoma associated with good prognostic parameters and it correlates well with response to hormone therapy. Although a lot of studies have been conducted in the past on hormone receptor expression in breast cancer and few have cor...

background and objective: breast cancer is the commonest cancer of indian women. estrogen and progesterone expression is seen in benign breast lesions and in breast carcinoma associated with good prognostic parameters and it correlates well with response to hormone therapy. although a lot of studies have been conducted in the past on hormone receptor expression in breast cancer and few have cor...

background: bcl-2 is the most important anti-apoptotic regulator and bax is a pro-apoptotic protein. the status of these parameters or the ration of bcl-2 to bax is important in malignant cell fate as well as normal cells. methods: sixty-two all patients and 62 healthy sex-and age-matched controls were studied. after genotyping, the promoter region of the bax and bcl-2 genes by rflp-pcr method ...

Liver cancer is the second most common cause of mortality among all cancers in the world. A holistic prognostic classification in hepatocellular carcinoma has not been unified yet. Many prognostic scoring systems have been made from different centres, some of which have been validated in large series. Even then, universally acceptable scoring systems are still an unmet need in this disease beca...

OBJECTIVE Myelodysplastic syndrome (MDS) is a clonal hematopoietic stem cell disease. Patients are at risk of developing cytopenias or progression to acute myeloid leukemia. Different classifications and prognostic scoring systems have been developed. The aim of this study was to compare the different prognostic scoring systems. MATERIALS AND METHODS One hundred and one patients who were diag...

Background and Aims: Myeloid cell leukemia-1 (Mcl-1) plays a pivotal role in the survival of hematologic and solid tumors, and is known as a substantial oncogene. Studies have demonstrated the altered expression of Mcl-1 has been linked to malignancy development and poor prognosis. In this research, we have studied the expression of Mcl-1 mRNA in myelodysplastic syndrome (MDS) patients and det...

STUDY DESIGN A retrospective study of 180 patients with lung cancer spinal metastases, wherein prognostic score-predicted survival was compared with actual survival. OBJECTIVE To evaluate and compare the accuracy of prognostic scoring systems in lung cancer spinal metastases. SUMMARY OF BACKGROUND DATA The modified Tokuhashi, Tomita, modified Bauer, and Oswestry scores are currently used to...

OBJECTIVES To assess the general applicability of prognostic scores for colorectal liver metastases (CRLM). METHODS Review of English language studies from 1980 to 2008 (Medline and Embase). Search keywords included "Colorectal neoplasms", "liver metastases", "liver resection", "prognostic scoring system". RESULTS Six scoring systems and fourteen prognostic factors within these studies were...