Purpose of review: Migraine attacks often follow prodrome symptoms. Prodrome symptoms are inconsistently and incompletely defined in literature. Here we define the functionality of the common prodrome symptoms and introduce additional ones that have so far eluded investigators. Prodrome types are not just symptoms but represent physiological changes that signal why a migraine may occur. Recent ...

OBJECTIVES To describe the onset pattern, frequency, and severity of the signs and symptoms of the prodrome of the first hypomanic/manic episode and first depressive episode of bipolar disorder (BD) and to investigate the influence of a history of childhood maltreatment on the expression of prodromal symptoms. METHODS Using a semi-structured interview, the Bipolar Prodrome Symptom Scale-Retro...

BACKGROUND The ability to differentiate chickenpox from smallpox is important for early recognition of bioterrorism events and prevention of false alarms. The febrile prodrome is a clinical feature used to differentiate these conditions. However, the prevalence of prodromal manifestations in chickenpox has not been well established. METHODS We evaluated prodrome characteristics of all chicken...

Introduction Commonly used syndromic surveillance methods based on the spatial scan statistic (1) first classify disease cases into broad, preexisting symptom categories (prodromes) such as respiratory or fever, then detect spatial clusters where the recent case count of some prodrome is unexpectedly high. Novel emerging infections may have very specific and anomalous symptoms, which should be ...

One of the conceptual difficulties faced by developmental psychopathologists is the plethora of terms for ‘things that predate the full manifestation of a psychiatric disorder.’ We have causes, vulnerabilities, susceptibilities, antecedents, risk factors, exposures, precursors, sub-threshold syndromes, and, of course, prodromes, the subject of this Annual Review. So we must first be clear what ...

CLINICAL HISTORY A 43-year-old woman has a history of recurrent migrainous headaches since aged 7 years. She develops blurred vision, goose bumps on her arms, slight nausea, clear nasal drainage, and a “tight” feeling in the right superior trapezius area, followed the next day by severe, incapacitating, right-sided headache with associated nausea and light sensitivity, lasting 3 days. These epi...

objective: schizophrenia and other psychoses have devastating personal and social impacts and many efforts have been devoted to study ‎prodromal syndromes for psychosis in order to achieve earlier detection and interventions. however, only few studies have been ‎performed in developing countries on this subject, and there is a dearth of evidence in the iranian population. in this study, we ‎foc...