orofacial pain can arise from different regions and etiologies. some of the most debilitating pain conditions arise from the structures innervated by the trigeminal system (head, face, masticatory musculature, temporomandibular joint and associated structures). the problem with referred pain is the misdiagnosis and unnecessary therapy directed to the pain location instead of its origin. when cr...

OBJECTIVES This study was undertaken to assess whether prodromal angina could have beneficial effects in diabetic patients with acute myocardial infarction (AMI). BACKGROUND Prodromal angina occurring shortly before the onset of AMI is associated with favorable outcomes by the mechanism of ischemic preconditioning. However, little is known about the impact of diabetes on ischemic precondition...

experience in a small and highly selected patient cohort with a remarkably low-risk profile and a very short time-to-treatment. There is a conflicting evidence about the prognostic significance of prodromal angina associated with pPCI, because someone found a better outcome (7), while others not (8,9). We documented that the additional infarct size reduction associated with prodromal angina tra...

According to the report of World Health Organization coronary artery disease every year has been considered as the leading death cause of more than 3.8 million men and 3.4 million women all over the world. Prodromal angina that occurs a short time before acute myocardial infarction onset has efficient protective effect in cardiovascular system with ischemic preconditioning but in conditions suc...

We recently found craniofacial pain to be the sole symptom of an acute myocardial infarction (AMI) in 4% of patients. We hypothesized that this scenario is also true for symptoms of prodromal (pre-infarction) angina. We studied 326 consecutive patients who experienced myocardial ischemia. Intra-individual variability analyses with respect to ECG findings and pain characteristics were performed ...

BACKGROUND Prodromal angina pectoris (AP) has a cardioprotective effect by the mechanism of ischemic preconditioning, and the QRS score on the admission electrocardiogram (ECG) reflects myocardial damage at presentation. This study was undertaken to investigate the effect of prodromal AP on infarct progression after the onset of acute myocardial infarction (AMI). METHODS AND RESULTS The study...

R ecently, the relation between coronary arterial remodelling and ischaemic coronary disease has become a focus of investigation. Positive coronary arterial remodelling has been shown to be more frequent in acute coronary syndromes, including acute myocardial infarction (AMI), whereas negative remodelling has been shown to be more frequent in stable angina. However, in the case of AMI, precedin...

Disease: Do They Exist? To the Editor: In the article “Women’s early warning symptoms of acute myocardial infarction,” Dr Jean McSweeney and coworkers1 renew the attention to prodromal symptoms of acute coronary events. In 1975, Alonzo et al2 observed that “unusual fatigue and weakness” were the most prevalent symptoms of myocardial infarction, followed by dyspnea and angina. Many authors repli...

INTRODUCTION AND OBJECTIVES The occurrence of preinfarction angina (PA) reduces the extent of myocardial necrosis, increases the volume of viable myocardium, and improves left ventricular function. However, there is no agreement about the effect of PA on mortality. The objective of this study was to determine whether PA is associated with in-hospital mortality. METHOD A meta-analysis (fixed e...