this study determined the clinical effect of subconjunctival administration of bevacizumab in patients with primary and recurrent pterygium. the study was an off-label, single-dosing, interventional case series involving 22 patients with primary and recurrent pterygium. they received subconjunctival bevacizumab (0.2cc). pterygium vascularity and thickness was graded. the size of the pterygium (...

purpose: to investigate the efficacy of limbal-conjunctival autografting technique in patients with primary pterygium methods: fifteen eyes of 15 patients with primary pterygium underwent surgery for the removal of pterygium with limbal-conjunctival autograft. after the pterygium excision, the limbal portion of the graft was oriented and sutured to the limbus at the recipient bed with the epith...

AIM To detect the presence of 8-hydroxydeoxyguanosine enzyme (8-OHdG) in recurrent pterygium and its role on recurrence. METHODS Ninty-two samples were collected of which 55 from primary pterygium, 12 from recurrent and 25 from normal conjunctiva. A cross sectional study was embarked to detect the presence of the 8-OHdG enzyme in primary, recurrent pterygium and the normal conjunctival tissue...

purpose: to report the result of limbal autografting in primary and recurrent pterygium. methods: in this case series, all patients who were referred to our clinic at farabi hospital, isfahan, iran for treatment of pterygium were included. indications of surgery included chronic ocular irritation, impaired or threatened vision, ocular motility problem and cosmetic reasons. under subconjunctiona...

PURPOSE To examine the expression pattern of insulin-like growth factor-binding protein (IGFBP)-2 in cultured primary pterygium fibroblasts and compare it with expression in normal conjunctival fibroblasts. METHODS Profile of gene expression by normal conjunctival and primary pterygium fibroblasts was performed by using a cDNA microarray. The overexpression of IGFBP-2 thus identified was furt...

purpose: to report subconjunctival injection of bevacizumab (avastin) for treatment of primary active pterygium. method: patients with primary active pterygia without other ocular disease, pregnancy or diabetes mellitus were enrolled. patients were randomly allocated into two groups to receive injection of avastin or placebo. patients were evaluated for changes in photophobia, conjunctival cong...

AIM To compare and evaluate the success rates of various surgical techniques of pterygium excision, including pterygium excision with complete suture of conjunctivae (PESC), pterygium excision with conjunctival auto-graft transplantation with graft from the inferior temporal bulbar conjunctiva (ITBC) and pterygium excision with conjunctival auto-graft transplantation with graft from the superio...

PURPOSE To evaluate DNA content and cellular proliferation rates in primary and recurrent pterygia. METHODS Matched pterygium and superior conjunctiva tissue were obtained in 36 eyes of 36 patients undergoing pterygium excision with conjunctival autografting (24 primary pterygia, 12 recurrent pterygia). Epithelial and fibrovascular layers were separated for analysis. Matched superior conjunct...

The purpose of this study was to evaluate the contribution of ultraviolet light (UV) as a causal factor of primary and pterygium recurrence. A conjuctival autograft transplantation was a surgical method of pterygium treatment. In the first group (38 eyes) were patients with primary and recurrent pterygium exposed to sun (worked outdoors), evaluating geodemographic status, and in the second grou...

We investigated relationships between outdoor air pollution and pterygium in Korean adults. This study includes 23,276 adults in population-based cross-sectional data using the Korea National Health and Nutrition Examination Survey 2008-2011. Pterygium was assessed using slit lamp biomicroscopy. Air pollution data (humidity, particulate matter with aerodynamic diameter less than 10 μm [PM₁₀], o...