objective(s):glaucoma is the second leading cause of blindness and it is related to oxidative stress based on numerous studies. glutathione s-transferases (gsts) are members of multigenic family, which have important role in cells as an antioxidant. in the present study, we examined the polymorphism of gstt1 and gstm1 deletion genotypes (t0m1, t1m0, and t0m0) in 100 glaucoma patients (41with pr...

purpose : to compare the serum homocysteine (hcy) level in healthy control individuals and in patient with primary open angle glaucoma (poag) and pseudoexfoliative glaucoma (pexg) methods : in this cross sectional study, 79 subjects including 36 patients with pexg, 23 patients with poag, and 20 matched healthy control individuals were recruited. those who used alcohol and mediations affecting h...

purpose: to evaluate visual outcomes and intraocular pressure (iop) after single-site phacotrabeculectomy with mitomycin c in patients with senile cataract and primary open angle glaucoma (poag), pseudoexfoliative glaucoma (pxg), or chronic angle closure glaucoma (cacg). methods: in this retrospective study, patients older than 50 years who had significant cataracts (bcva £ 20/60) and uncontrol...

Objective(s):Glaucoma is the second leading cause of blindness and it is related to oxidative stress based on numerous studies. Glutathione S-transferases (GSTs) are members of multigenic family, which have important role in cells as an antioxidant. In the present study, we examined the polymorphism of GSTT1 and GSTM1 deletion genotypes (T0M1, T1M0, and T0M0) in 100 Glaucoma patients (41with pr...

background: glaucomatous neuropathy is a type of cell death due to apoptosis. the p53 gene is one of the regulatory genes of apoptosis. recently, the association between the p53 gene encoding for proline at codon 72 and primary open-angle glaucoma (poag) has been studied in some ethnic groups. this study is the first association analysis of poag and p53 codon 72 polymorphism in iranian patients...

glaucoma is a major cause of blindness worldwide. a single nucleotide polymorphism of the mthfr gene (c677t) has been associated with susceptibility to this disease, although this is controversial in the last decade. in this study, the possible association between the mthfr c677t polymorphism and the risk of developing primary open angle (poag) and pseudoexfoliation glaucoma (pexg) was investig...

Background: Glaucoma is a progressive optic neuropathy and is one of the leading causes of blindness worldwide. Different factors have been contributed in the pathogenesis of glaucoma including H. pylori infection. Objective: To determine the levels of anti-H. pylori IgG antibody in the aqueous humor of patients with pseudoexfoliation and primary open angle glaucoma, in comparison with age and ...

Background: Glaucoma is one of the most common causes of blindness and is usually associated with elevated intraocular pressure. In patients with primary open angle glau-coma the number of trabecular meshwork cells is decreased. Death of the trabecular meshwork cells may be a result of apoptosis. Objective: To investigate the aqueous humor levels of soluble Fas (sFas) and Fas-Ligand (sFasL) in ...

purpose: the objective of this study was to identify possible risk factors associated with primary open-angle glaucoma (poag). methods: a case-control study included patients seen at rasoul-akram hospital ophthalmology clinic. cases were consecutive patients with confirmed unilateral or bilateral poag presented during the study period. controls were a random sample of all other patients aged 30...

Fifty-nine eyes undergoing combined cataract extraction and trabeculectomy were studied. The follow-up period ranged from 6 months to 2 years. The visual outcome and postoperative control of intraocular pressure have been compared in chronic open-angle, chronic closed-angle, and secondary glaucoma. Good results were obtained in both primary open- and closed-angle glaucoma, but not in secondary ...