preterm birth means the birth before thirty seven week of pregnancy that causes a lot of complications for the baby. variety factors are suggested to be involved in disease. in this study, we decided to evaluate haptoglobin (hp) phenotypes association with clinical features of patients suffered from premature delivery to understand better the possible correlation of genetic and clinical feature...

background: preterm labor (ptl) is the main challenge in prenatal health care, leads to high rate of mortality and  increases cost of health services. to evaluate the preterm delivery (ptd)?related risk factors, we decided to measure nitrite oxide metabolites and cervical length (cl) as the diagnostic and predictive tools for ptd in women and response to tocolytic therapy.materials and methods:...

introduction: considering the high incidence of preterm labor and its known complications, and that human myometrium contains receptors for human chronic gonadotropin (hcg) and that hcg can inhibit myometrial contractions on vitro, made me study treating effects of hcg on preterm labor. this clinical trial study was carried out to compare the effect of hcg, and magnesium sulfate (mgso4) on prev...

background: vaginal bleeding is a common complication during pregnancy, which is observed in about 1/4 of pregnancies and in half of cases can lead to abortion. if vaginal bleeding happens during pregnancy some adverse pregnancy outcomes, including perinatal mortality and morbidity, low birth weight and preterm delivery will be increased. objective:  the aim of this study was to determine the r...

objective : the study evaluated the efficacy and safety of vaginal rogesterone on prevention of recurrent preterm labor. materials and methods: total number of 70 patients with preterm labor treated with intravenous magnesium sulfate in perinatology department of valiasr hospital entered to a randomized clinical trial. treatment group after inhibition of preterm labor with magnesium sulfate rec...

at present, many drugs are used for inhibition of uterine contractions, but the proportions of preterm labors are increasing. although magnesium sulfate is the most commonly prescribed parenteral tocolytic agent, but it’s optimal use has yet to be delineated. in this study a high-dose protocol for magnesium sulfate tocolytic therapy was compared with a low-dose regimen. one hundred patients adm...

background and objective: preterm birth occurs in 8% to 11% of all pregnancies and is responsible for 75% to 80% of all neonatal deaths. cytokines may be involved in the etiology of preterm birth through their stimulation of prostaglandin synthesis. cytokines may be released intocervicovaginal fluid during the breakdown of the chorio-decidual adhesion or from an inflammatory reaction in the sam...

background: preterm labor is the leading cause of infant morbidity and mortality so it may be necessary to administer tocolytics for treatment of it. objective: the aim of this study was to compare the efficacy and safety of magnesium sulfate and nifedipine in the management of preterm labor. materials and methods: 100 women with documented preterm labor were randomly assigned to receive magnes...

regarding to prevalence of preterm labor and its consequences, there are different reports on relationship between bacterial vaginosis and preterm labor. this study was performed to evaluate the effect of metronidazole therapy on preterm labor in women with bacterial vaginosis. this randomized clinical trial was performed on 120 women suffering from bacterial vaginosis at 20-34 weeks of pregnan...