shadab salehpour assistant professor of pediatric endocrinology and fellowship of bone and inherited metabolic disorders,shahid beheshti university of medical sciences, tehan ,iran farzaneh rohani assistant professor of pediatric endocrinology, tehran university of medical sciences, tehran, iran omid aryani senior researcher, molecular genetics, department of medical genetics, special medical center, tehran, iran massoud houshmand assistant professor of human genetics, department of medical genetics, national institute of genetic engineering and biotechnology (nigeb), tehran, iran farhad hasheminezhad pulmonologist, tehran, iran morteza rezvani kashani pediatric neurologist, tehran, iran