oral submucous fibrosis is chronic progressive condition of oral cavity. the condition is well recognized for its malignant potential. usually the disease initiates with redness, blistering, and ulceration inside the mouth. it is characterized by progressive fibrosis of submucosal tissue. the pathogenesis of oral submucous fibrosis is not well understood. betelquid chewing is the major etiologi...

many types of cancers develop in the oral and maxillofacial region. squamous cell carcinoma is the most common cancer and constitutes over 90 percent of these tumors. malignant transformation is a genetic process, which later makes a phenotyping change at the cellular level. some cancers such as oral squamous cell carcinomas (osccs) develop from pre-malignant lesions and conditions. despite adv...

An evaluation of the malignant potential of submucous fibrosis, based on observations of 89 patients with the disease in Ernakulam District, Kerala, India was done. Out of the 89 patients, 12 were referred patients and 77 were diagnosed in population based studies. At the time of first examination oral cancer was found to be coexistent in nine (10%) cases. For 66 patients follow-up observations...

Method: Two hundred and nine patients who were diagnosed with precancerous lesions and referred to the dermatology department of Imam Reza hospital from 1997 to 2007 were studied. Study parameters included participants’ age, sex and occupation, type of precancerous skin lesion, clinicopathological type of the lesion and location. The data was collected from the patients’ records in the dermatol...

Gastric carcinoma is a common malignant disease associated with an unfavorable prognosis in the case of late dia-gnosis. The most significant precancerous condition is chronic atrophic gastritis and intestinal metaplasia caused by Helicobacter pylori infection. These longlasting changes may lead to formation of dysplastic precancerous lesions. Upper endoscopy and histologic examination of force...