نتایج جستجو برای: preantral follicle

تعداد نتایج: 21081  

Journal: :Endocrinology 2009
Makoto Orisaka Jin-Yi Jiang Sanae Orisaka Fumikazu Kotsuji Benjamin K Tsang

The transition from preantral to early antral stage is the penultimate stage of ovarian follicular development in terms of gonadotropin dependence and follicle destiny. Although oocyte-somatic cell communication is important in early follicular development, our knowledge of the precise role of the oocyte-derived growth differentiation factor (GDF)-9 during preantral follicle growth is incomplet...

Journal: :Endocrinology 1997
Elizabeth McGee Norah Spears Sawako Minami Sheau-Yu Hsu Sang-Young Chun Ha Kan Billig Aaron J W Hsueh

Progression of preantral follicle development is essential to further follicle maturation and ovulation, but there are few models for studying the regulation of preantral follicle survival and growth. We have evaluated preantral follicle survival in vivo and in vitro, and have developed a serum-free rat follicle culture system that can be used to characterize the regulation of preantral follicl...

2013
Cheng Zhang Xiaoxia Wang Zhengpin Wang Wanbao Niu Baochang Zhu Guoliang Xia

The mechanical method to isolate preantral follicle has been reported for many years. However, the culture systems in vitro are still unstable. The aim of this study was to analyze the effect of the culture system of mice preantral follicles on the follicular development in vitro. The results showed that the 96-well plate system was the most effective method for mice follicle development in vit...

2013
Shuichiro Hara Toshifumi Takahashi Mitsuyoshi Amita Koki Matsuo Hideki Igarashi Hirohisa Kurachi

BACKGROUND Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age and is characterized by chronic anovulation. Insulin resistance may be a key component of the pathogenesis of this disorder. Pioglitazone is a thiazolidinedione derivative that acts by improving insulin resistance via the peroxisome proliferator-activated receptor-γ (PPAR-γ) pathway. Reported...

2014
Valdevane R Araújo Melba O Gastal José R Figueiredo Eduardo L Gastal

Preantral follicles are the majority of the ovarian follicle population and their use as a source of homogeneous oocytes for bovine reproductive biotechnologies could result in a substantial advance in this field. However, while in other species embryos and offspring have been produced, in bovine species the results have been limited to the follicular activation of small (primordial) preantral ...

Journal: :Journal of Ovarian Research 2009
Makoto Orisaka Kimihisa Tajima Benjamin K Tsang Fumikazu Kotsuji

The preantral-early antral follicle transition is the penultimate stage of follicular development in terms of gonadotropin dependence and follicle destiny (growth versus atresia). Follicular growth during this period is tightly regulated by oocyte-granulosa-theca cell interactions. Formation of the theca cell layer is a key event that occurs during this transitional stage. Granulosal factor(s) ...

2017
G D A Gastal A Hamilton B G Alves S G S de Tarso J M Feugang W J Banz G A Apgar C K Nielsen E L Gastal

The knowledge about ovarian reserve is essential to determine the reproductive potential and to improve the methods of fertility control for overpopulated species, such as white-tailed deer (Odocoileus virginianus). The goal of this study was to evaluate the effect of age on the female reproductive tract of white-tailed deer, focusing on ovarian features. Genital tracts from 8 prepubertal and 1...

2012
Byung Chul Jee Jee Hyun Kim Da Hyun Park Hyewon Youm Chang Suk Suh Seok Hyun Kim

OBJECTIVE To determine whether animal age impacts in vitro preantral follicle growth. Effects of hCG, stem cell factor (SCF), and/or insulin-like growth factor (IGF) supplementation in growth medium were also investigated. METHODS Intact preantral follicles were mechanically isolated from fresh ovaries of BDF1 mice and cultured in growth medium for 9 to 11 days. Surviving follicles with antru...

Journal: :Mutagenesis 2005
Fengyun Sun Ilse Betzendahl Francesca Pacchierotti Roberto Ranaldi Johan Smitz Rita Cortvrindt Ursula Eichenlaub-Ritter

Aneuploidy tests are important in evaluating genetic hazards especially when chemical exposures are suspected to affect the fidelity of chromosome segregation in oocytes and embryos. In the current study, a newly established method, mouse preantral follicle culture, was employed to grow oocytes in vitro within follicles. The sensitivity of in vitro grown follicle enclosed oocytes was compared w...

Journal: :Endocrine reviews 2015
Aaron J W Hsueh Kazuhiro Kawamura Yuan Cheng Bart C J M Fauser

Although hormonal regulation of ovarian follicle development has been extensively investigated, most studies concentrate on the development of early antral follicles to the preovulatory stage, leading to the successful use of exogenous FSH for infertility treatment. Accumulating data indicate that preantral follicles are under stringent regulation by FSH and local intraovarian factors, thus pro...

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