Objective: We have previously demonstrated that myocardium is capable of down-regulating its 0, requirements and thus avoiding ischaemia when 0, supply is limited. The present study tested the hypothesis that endogenous adenosine produced this protective response when 0, supply was decreased by moderate coronary hypoperfusion or moderate coronary hypoxaemia. Methods: In anaesthetised dogs, hear...

Microprocessors have long employed caches to help hide the increasing latency of accessing main memory. The vast majority of previous research has focussed on increasing cache hit rates to improve cache performance, while lately decreasing power consumption has become an equally important issue. This thesis examines the lifetime of cache lines in the memory hierarchy, considering whether they a...

CONTEXT In the South African mining sector, cardiorespiratory-specific autopsies are conducted under the Occupational Diseases in Mines and Works Act (ODMWA) on deceased mineworkers to determine eligibility for compensation. However, low levels of autopsy utilisation undermine the value of the service. OBJECTIVE To explore enablers and barriers to consent that impact on ODMWA autopsy utilisat...

Background Despite numerous efforts to improve maternal and child health in Malawi, maternal and newborn mortality rates remain very high, with the country having one of the highest maternal mortality ratios globally. The aim of this study was to identify which individual factors best predict utilisation of skilled maternal healthcare in a sample of women residing in Lilongwe district of ...

Introduction: Note taking while attending a PPT requires highactivity of memory and writing process which ultimately leadsto what is called “death by power point” referring to boredomand fatigue. To overcome this we planned to evaluate the impactof utilisation of uncompleted handouts given prior to PPTpresentations.Methods: Final year MBBS students were divided in 2 batches,batch A and batch B....

health systems across the world are concerned with the quality and safety of patient care. this includes investing in research and development to progress advances in the treatment and management of individuals and healthcare organisations. the concept of evidence- based healthcare has gained increasing currency over the last two decades; yet questions persist about the time it takes for new re...