Object-oriented databases have limited support for evolution at the schema level. This paper presents a framework for transparent class evolution and integration, which unifies existing evolution techniques, like subclassing, generalisation, class versioning, and integration by views. The transparency offered allows existing and new clients of classes to be unchanged upon evolution and integrat...

Alternative splicing of pre-mRNA is a mechanism that increases the protein diversity of a single gene by differential exon inclusion/exclusion during post-transcriptional processing. While alternative splicing is established to occur during lymphocyte activation, little is known about the role it plays during the immune response. Our study is among the first reports of a systematic genome-wide ...

The development of internetlinked classes in small schools in Canada has been facilitated by school district digital intranets. These electronic structures that link schools, together with the teaching and learning processes that take place within them, have demonstrated the possibilities of integrating virtual and actual teaching and learning. Cybercells – face to face groups in which members ...

Loops are regions of non-repetitive conformation connecting regular secondary structures. They are both the most difficult and error prone regions of a protein to solve by X-ray crystallography and the hardest regions to model using knowledge-based procedures. While the core of a protein can be straight forwardly modelled from the structurally conserved regions of homologues of known structure,...

The closure property is essential to enhance the power of database languages. In the deductive object-oriented database (DOOD) context, this property implies that the rule-derived objects as well as the rule-derived classes (i.e. the classes populated by the derived objects) be established with full OO (objectoriented) features. This paper provides the methods of specifying the OO features of d...

An approach is presented to the automatic discovery of labels of relations between pairs of ontological classes. Using a hyperlinked encyclopaedic resource, we gather evidence for likely predicative labels by searching for sentences that describe relations between terms. The terms are instances of the pair of ontological classes under consideration, drawn from a populated knowledge base. Verbs ...

 Active networking aims at transforming passive data carriers to active, dynamically configurable machines that no only pass data to each other but also perform computation on those data. In such a framework mobile agents can help either as carriers of the active code to be installed on active nodes or even as actors by managing the node autonomously. This paper explores the applicability of t...